Objective: To introduce capped biparametric (bp) MRI slots for follow-up imaging of prostate cancer patients enrolled in active surveillance (AS) and evaluate the effect on weekly variation in the number of AS cases and total MRI workload.
Methods: Three 20 min bpMRI AS slots on two separate days were introduced at Addenbrooke's Hospital, Cambridge. The weekly numbers of total prostate MRIs and AS cases recorded 15 months before and after the change (Groups 1 and 2, respectively). An intergroup variation in the weekly scan numbers was assessed using the coefficient of variance (CV) and mean absolute deviation; the Mann-Whitney test was used for an intergroup comparison of the latter.
Results: In AS patients, a shift from considerable to moderate variation in weekly scan numbers was observed between the two groups (CV, 51.7 and 26.8%, respectively); mean absolute deviation of AS scans also demonstrated a significant decrease in Group 2 (1.28 2.58 in Group 1; < 0.001). No significant changes in the variation in total prostate MRIs were observed, despite a 10% increased workload in Group 2.
Conclusion: A significant reduction in weekly variation of AS cases was demonstrated following the introduction of capped bpMRI slots, which can be used for more accurate long-term planning of MRI workload.
Advances In Knowledge: The paper illustrates the potential of introducing capped AS MRI slots using a bp protocol to reduce weekly variation in demand and allow for optimising workflow, which will be increasingly important as the demands on radiology departments increase worldwide.
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http://dx.doi.org/10.1259/bjr.20190929 | DOI Listing |
Qual Health Res
January 2025
Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.
is a free, weekly organized mass participation physical activity event providing a remarkable example of at-scale dissemination, with over 1 million participants and 150,000 volunteers in Australia. This qualitative study draws on stakeholders' experiences to explore how succeeded with its dissemination and sustainability in Australia. Maximum variation and snowball sampling methods were used to select interviewees representing three stakeholder groups: Australia employees; volunteer organizers (event directors and ambassadors); and local external stakeholders (e.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Cuisine and Nutrition, School of Tourism and Cuisine, Yangzhou University, Yangzhou, China.
In addition to being linked to an excess of lipid accumulation in the liver, being overweight or obese can also result in disorders of lipid metabolism. There is limited understanding regarding whether different levels of protein intake within an energy-restricted diet affect liver lipid metabolism in overweight and obese rats and whether these effects differ by gender, despite the fact that both high protein intake and calorie restriction can improve intrahepatic lipid. The purpose of this study is to explore the effects and mechanisms of different protein intakes within a calorie-restricted diet on liver lipid metabolism, and to investigate whether these effects exhibit gender differences.
View Article and Find Full Text PDFJ Surg Educ
January 2025
Cleveland Clinic Lerner College of Medicine Orthopaedic and Rheumatology Insititute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, Ohio 44195. Electronic address:
Introduction: Medical education imposes a financial burden on trainees. Given that cost-of-living varies across geographical regions, understanding its relationship with resident compensation can inform about the finances of residents. We investigated: (1) How does compensation for orthopaedic surgery residents vary across regions? (2) How does compensation for orthopaedic surgery residents vary with respect to cost of living? (3) What is the extent of surplus income for residents after accounting for hours worked? (4) What are the predictors of annual income for orthopaedic residents?
Material And Methods: Using the American Medical Association FREIDA database, we collected weekly work hours, location, program type, moonlight allowance, and geographic region for 190 nonmilitary orthopaedic programs.
Am J Cardiovasc Drugs
January 2025
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, 3875 Holman St., Houston, TX, 77204-6015, USA.
Background: It remains controversial whether exercise training (EX) improves vascular endothelial function (VEF) independent of lipoprotein changes even though these are therapeutic goals for coronary artery disease (CAD).
Objective: The purpose of this study was to systematically review the effects of EX on VEF and blood lipid variables in patients with CAD.
Methods: This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.
J Therm Biol
January 2025
Department of Biology, Trent University, Peterborough, ON, K9J 1Z8, Canada; Environmental and Life Sciences Graduate Program, Trent University, Peterborough, ON, K9J 5G7, Canada. Electronic address:
Critical thermal maximum (CT) is the most widely used method for quantifying acute upper thermal limits in ectotherms. CT protocol exposes animals to a consistent rate of environmental warming until they lose motor function. CT has been used to assess intraspecific variation among life stages, populations, or as a function of body size, often with the assumption that it is a durable and heritable trait at the individual level.
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