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[Current Consensus and Challenges of Fluorescence Imaging Technology in the Surgery of Spinal Intramedullary Tumors].
No Shinkei Geka
January 2025
Department of Neurosurgery, Osaka Medical and Pharmaceutical University.
Surgery for spinal intramedullary tumors remains a major challenge for neurosurgeons. Successful surgery requires experience, skill, and intraoperative imaging support. Fluorescence imaging technology has become a valuable support in neurosurgical procedures of not only the brain but also the spinal cord.
View Article and Find Full Text PDFNucleolin-targeted silicon-based nanoparticles for enhanced chemo-sonodynamic therapy of diffuse large B-cell lymphoma.
Int J Pharm
January 2025
Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361005, China. Electronic address:
The limited selectivity and high systemic toxicity of traditional chemotherapy hinder its efficacy in treating diffuse large B-cell lymphoma (DLBCL). The combination of sonodynamic therapy (SDT) with chemotherapy has emerged as a novel strategy for cancer treatment, aiming to improve therapeutic outcomes and reduce systemic toxicity. However, challenges such as elevated drug clearance rates and non-selecitivity remain to be resolved.
View Article and Find Full Text PDFWill indocyanine green shed light on accessory cavitated uterine malformations?
Fertil Steril
January 2025
Massachusetts General Hospital Fertility Center - Massachusetts General Hospital and Harvard Medical School, Department of Obstetrics/Gynecology and Reproductive Biology, Division of Reproductive Endocrinology and Infertility, Boston, MA, USA.
Postoperative and permanent hypocalcemia after indocyanine green (ICG) angiography-guided total thyroidectomy and central neck dissection: A retrospective cohort study.
Surgery
January 2025
Service of Digestive and General Surgery, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Background: This study aimed to compare the rates of postoperative and permanent hypocalcemia between postthyroidectomy indocyanine green angiography and indocyanine green angiography-guided thyroidectomy performed intraoperatively for identification and preservation of the parathyroids.
Methods: We undertook a retrospective study of 2 cohorts of patients with thyroid cancer undergoing total thyroidectomy and central neck dissection. The first cohort (control group) included patients who underwent postthyroidectomy indocyanine green angiography to predict parathyroid function by scoring the degree of fluorescence (0, black; nonvascularized; 1, gray/heterogeneous: partially vascularized; and 2, white: well vascularized), and the second cohort (angiography-guided thyroidectomy) included patients undergoing initially indocyanine green angiography-guided thyroidectomy to identify the feeding vessels of the parathyroid glands followed by postthyroidectomy indocyanine green angiography.
Indocyanine Green Angiography-Assisted Marsupialization of a Petrous Apex Cholesterol Granuloma: 2-Dimensional Operative Video.
Oper Neurosurg (Hagerstown)
November 2024
Department of Neurosurgery, School of Medicine, University of California San Francisco, San Francisco, California, USA.
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