Background/objectives: To determine if the presence of sub-retinal fluid (SRF) was associated with reduced vision in dome-shaped macula (DSM), and to assess its effect and response to treatment during follow-up.
Methods: Patients were identified retrospectively. Baseline and follow-up data were recorded. The diagnosis of DSM, and presence or absence of SRF and intra-retinal fluid (IRF) was confirmed using Spectral Domain-Optical Coherence Tomography (SD-OCT). Decisions to treat oedema were based on clinician preference.
Results: 193 eyes of 106 patients (71 female) were confirmed to have DSM. Overall mean duration of follow-up for this cohort was 3.5 years. Mean BRVA for all eyes at baseline was 0.38 (range: -0.20 to 'light perception'). A significant difference was noted in mean baseline BRVA between those eyes with SRF compared with those without SRF at baseline (0.48 vs. 0.31, p < 0.001). Intra-retinal fluid moderately correlated with poorer baseline BRVA (r = 0.31, p < 0.003). No significant change in BRVA was noted during follow-up. No significant effect of treatment on BRVA was observed.
Conclusions: The presence of SRF at baseline was associated with poorer vision. Vision appears to remain stable irrespective of the presence or absence of SRF at baseline. The treatments administered in this cohort did not affect final vision or SRF.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608413 | PMC |
| http://dx.doi.org/10.1038/s41433-020-0769-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical and anatomical features of myopia.
Asia Pac J Ophthalmol (Phila)
December 2024
Department of Ophthalmology, Faculty of Medicine, University of Cologne, University Hospital Cologne, Cologne, Germany.
Article Synopsis
- The review summarizes the clinical and anatomical aspects of myopia, highlighting the different stages of myopic maculopathy (MMP) and their association with retinal changes.
- Recent findings show that MMP stage-4 is linked to defects in Bruch's membrane and previous macular neovascularization, while stage-3 demonstrates differences based on the presence of these defects.
- Additionally, higher axial lengths in myopic eyes correlate with increased risks for vision loss and certain eye conditions, including open-angle glaucoma, emphasizing the complexity and implications of myopia in aging populations.
A case of acute idiopathic maculopathy in both eyes with peripheral vascular occlusion.
BMC Ophthalmol
November 2024
Beijing Tongren Hospital, Capital Medical University, Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, 00730, China.
Background: This study aimed to present a case of bilateral symmetric onset of acute idiopathic maculopathy after high fever with peripheral vascular occlusion.
Case Presentation: A 54-year-old yellow female experienced acute binocular visual acuity decrease after 1 day of high fever, and binocular visual acuity decreased to index or anterior. OCT in the external hospital showed dome-shaped cortical detachment in the symmetrical macular area of both eyes with subretinal fluid, discontinuity in the ellipsoid zone and the chimera.
Semi-Automated Analysis of Dome-Shaped Macula in Preterm and Full-Term Infants Using Handheld Swept-Source Optical Coherence Tomography.
Invest Ophthalmol Vis Sci
October 2024
Division of Ophthalmology, Seattle Children's Hospital, Seattle, Washington, United States.
Article Synopsis
- The study investigates dome-shaped macula (DSM) in preterm and full-term infants using advanced optical imaging technology, highlighting increased occurrence in preterm infants.
- Out of 217 imaging sessions, DSM was found in 40% of preterm infants compared to 14% of full-term infants, showing a significant difference in diagnosis timing and dome characteristics.
- The results suggest that while DSM is common in infants and typically round in shape, it isn't linked to macular fluid presence, indicating unique differences from DSM in older children and adults.
Comparison of visual acuity outcome and choroidal thickness variation of intravitreal ranibizumab injection for myopic choroidal neovascularization with or without dome-shaped macula.
Photodiagnosis Photodyn Ther
December 2024
Department of Ophthalmology, The Second People's Hospital of Foshan, Foshan 528000, China.
Background: To investigate the visual acuity outcome and choroid thickness (CT) change after intravitreal ranibizumab in highly myopic eyes with or without dome-shaped macula (DSM) in Chinese patients.
Methods: This retrospective, observative study included 80 treatment-naive eyes (80 patients), which received ranibizumab according to the 1+PRN protocol. The best corrective visual acuity (BCVA) and CT change were compared between eyes with or without DSM.
Prevalence and associations of dome-shaped maculas. The Beijing Eye Study.
Acta Ophthalmol
September 2024
Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Article Synopsis
- The study investigates the occurrence of dome-shaped maculas (DSMs) in a diverse population, focusing on those with different axial lengths of the eye.
- Out of 3468 participants, DSMs were found in 1.9% of examined eyes, with a notable increase in prevalence among highly myopic individuals (7.2%).
- Results suggest that longer axial lengths and more advanced myopic macular degeneration are linked to higher DSM prevalence and height, indicating potential underlying factors related to eye elongation and retinal health.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!