AI Article Synopsis
- Researchers evaluated whether low-reacting mice could be transformed into high-reacting ones using natural immunostimulators like L-tyrosine and thymic polypeptides (taktivin).
- L-tyrosine was found to effectively promote phenotypical correction in the immune response of low-reacting mice.
- A significant increase in antibody-forming cells (AFC) and AFC-SI secreting IgM was observed in low-reacting mice after treatment, compared to high-reacting mice.
Article Abstract
The possibility of transversion of low-reacting mice into high-reacting ones evaluated by the application of the natural immunostimulators. L-tyrosine and thymic polypeptides (taktivin) were compared by their ability for the phenotypical correction of the immune response of the oppositely reacting mice. It was established that under the application of L-tyrosine to oppositely reacting mice the phenotypical correction of the immune response is possible. The dramatic increase in AFC and the AFC-SI secreting IgM is observed in the mice, low-reacting to SRBC in comparison with the high-reacting lines.
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