Huge accessory spleen (AS) is a rare condition difficult to diagnose. We recently treated a Japanese woman with a progressive huge AS. She had a history of aortic valve replacement for aortic stenosis 1 month prior. At that time, a 4-cm AS had been detected by the preoperative computed tomography (CT). This mass was a progressive tumor which grew to 7 cm over the course of 3 months. Thus, we performed surgery with a preoperative diagnosis of huge AS by CT and positron emission tomography. A laparoscopic resection was performed considering the risk of torsion, spontaneous rupture, or hemorrhage. The final pathological diagnosis was AS. This is the first reported case in the English literature of progressive AS with no symptoms at the initial presentation that was treated with laparoscopic resection.
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http://dx.doi.org/10.1159/000504433 | DOI Listing |
Wearable sensors with multiple functions are attracting significant attention due to their broad applications in health monitoring and human-computer interaction. Despite significant progress in wearable sensors, it is a significant challenge to monitor temperature and stress simultaneously with a single sensor. A wearable multifunctional optical sensor based on Er/Yb co-doped GdO nanoparticles and a tapered U-shaped fiber is proposed to monitor both temperature and stress in this paper.
View Article and Find Full Text PDFAnal Biochem
January 2025
Jianhu Clinical Medical College of Yangzhou University, Jianhu, Jiangsu, China, 224700. Electronic address:
In this study, we emphasize the importance of identifying Let-7a, a microRNA that is key in diagnosing and predicting lung cancer outcomes. Let-7a's function as a biomarker is essential, as it affects tumor suppression and controls cell differentiation and growth. We developed a novel device, an electrochemical biosensor based on Duplex Specific Nuclease (DSN), that is designed for the accurate detection of Let-7a.
View Article and Find Full Text PDFJ Prev Alzheimers Dis
January 2025
Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Background: Atrial fibrillation (AF) has been associated with elevated dementia risk, while few studies have examined the role of the optimal glycemic status in disease trajectories of AF and dementia.
Objectives: We aim to evaluate associations between glycemic status with disease trajectories of AF and dementia, as well as major dementia subtypes, including Alzheimer's disease and vascular dementia.
Design: Population-based cohort study.
Osteoarthritis (OA) is a degenerative joint disease that affects the entire joint and has been a huge burden on the health care system worldwide. Although traditional therapy and targeted cartilage cell therapy have made significant progress in the treatment of OA and cartilage regeneration, there are still many problems. Mesenchymal stem cells from various tissues are the most studied cell type and have been used in preclinical and clinical studies of OA, because they are more widely available, have a greater capacity for in expansion, and have anti-inflammatory and immunomodulatory properties compared to autologous chondrocytes.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Department of Information Management, Tunghai University, Taichung 407224, Taiwan.
Today, huge amounts of time series data are sensed continuously by AIoT devices, transmitted to edge nodes, and to data centers. It costs a lot of energy to transmit these data, store them, and process them. Data compression technologies are commonly used to reduce the data size and thus save energy.
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