Benign prostatic hyperplasia (BPH) is a common disease in elderly men. Transurethral resection of the prostate (TURP) is still the standard treatment for BPH. However, postoperative urinary incontinence (UI) is still one of the complications. This study aims to evaluate the clinical efficacy and safety of the TURP by traditional compared with preserved urethral mucosa of the prostatic apex (PUMPA). From July 2015 to June 2016, 80 patients with TURP were included and divided into the two groups: traditional nonpreserved urethral mucosa group (TURP group, = 40) and the PUMPA group (PUMPA-TURP group, = 40). This study identified the apex of the prostate and determined the cut position of mucosa. Then, we separated the preserved urethral mucosa, excised the hyperplastic prostate tissue, and trimmed the preserved urethral mucosa. The rate of UI after PUMPA-TURP was significantly lower than that traditional TURP (0% 22.5%). The operative time was significantly shorter in the PUMPA-TURP group than traditional TURP group (50 ± 16.5 minutes 65 ± 18.5 minutes). The intraoperative bleeding loss was lower in the PUMPA-TURP group than traditional TURP group (280 ± 33 mL 190 ± 35 mL). International prostate symptom score, quality of life (QoL), and peak uroflowmetry data (Qmax) were similar between two groups. When compared with traditional TURP, PUMPA-TURP can reduce the occurrence of UI and intraoperative blood loss. Besides, PUMPA-TURP could shorten the operative time.
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http://dx.doi.org/10.1089/end.2019.0804 | DOI Listing |
World J Urol
January 2025
Department of Urology, Zhangjiagang Hospital Affiliated to Soochow University, Suzhou, Jiangsu, China.
Purpose: The purpose of this study was to investigate the efficacy of Transurethral Holmium Laser of the Prostate (HoLEP) with Double-n Technology in the treatment of benign prostatic hyperplasia (BPH), with a focus on preserving sexual function postoperatively.
Methods: Conducted as a multicenter, prospective, single-blind randomized controlled trial, this study enrolled sexually active male patients with BPH. Participants were randomized into three groups: standard HoLEP (Group A), single-n technology (Group B), and innovative double-n technology (Group C), which emphasizes the preservation of the urethral mucosa and nearby structures.
J Pediatr Urol
December 2024
Department of Pediatric Surgery and Urology, Medical University of Silesia, ul. Medyków 16, 40-752, Katowice, Poland.
Introduction: Epidermolysis bullosa (EB) can severely affect the urinary tract, leading to strictures and urine outflow obstruction, which pose significant risks to kidney function. Procedures involving the urinary mucosa often exacerbate these issues, making safe bladder emptying a major challenge. This study reviews surgical methods for managing urological complications in EB patients, with a focus on the Macedo procedure, which offers a promising alternative that avoids further bladder mucosa irritation and prevents disease exacerbation.
View Article and Find Full Text PDFAm J Vet Res
January 2025
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO.
Objective: To document differences in the microbiota of healthy cats versus cats with urethral obstruction (UO); compare the urinary microbiota with the oral, preputial, and rectal microbiota; and demonstrate that 16S rRNA gene sequencing will reveal rich and diverse urinary microbiota.
Methods: 15 client-owned cats with UO and 15 age-matched healthy cats were included from July 2020 through April 2021. Exclusion criteria were evidence of urinary tract infection, urolithiasis, antimicrobial administration, urinary catheterization in the past 30 days, or a comorbidity.
Cureus
December 2024
Department of Dermatology, Beaumont Hospital, Dublin, IRL.
This case report describes Zoon's vulvitis or plasma cell vulvitis (PCV) with coexisting lichen planus (LP) treated with methotrexate. PCV is a rare, chronic, benign idiopathic inflammatory condition of the vulvar mucosa, characterized by a bright-red, chronic lesion of mucosa. Typically, it presents as atrophic, shiny, red plaques that can affect any part of the vulva and can spread symmetrically and bilaterally with the propensity of chronicity and gradual coalescence.
View Article and Find Full Text PDFInt Braz J Urol
December 2024
Serviço de Urologia - Hospital Federal da Lagoa, Rio de Janeiro, RJ, Brasil.
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