The structure and the synthesis of the blood-glucose lowering sulfonylurea glimepiride (Hoe 490) and of some analogues is described. The acylureido group of these compounds is prepared from lactams.
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Acylureidoalkylphenylsulfonylureas with blood glucose lowering efficacy.
Arzneimittelforschung
August 1988
Hoechst Aktiengesellschaft, Frankfurt/Main, Fed. Rep. of Germany.
The structure and the synthesis of the blood-glucose lowering sulfonylurea glimepiride (Hoe 490) and of some analogues is described. The acylureido group of these compounds is prepared from lactams.
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