The Effects of Bariatric Surgery and Endoscopic Bariatric Therapies on GERD: An Update.

Curr Treat Options Gastroenterol

Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Published: March 2020

AI Article Synopsis

  • Bariatric surgery, including procedures like sleeve gastrectomy and Roux-en-Y gastric bypass, is increasingly used to treat obesity but can negatively impact gastroesophageal reflux disease (GERD).
  • Recent evidence indicates sleeve gastrectomy has the highest rates of new GERD cases, while Roux-en-Y gastric bypass and one anastomosis gastric bypass show lower rates; intragastric balloons are also linked to increased GERD risks.
  • Patients considering bariatric surgery might benefit from an endoscopy before the procedure to select the best treatment option, and more research is needed to understand the effects of surgeries like endoscopic sleeve gastroplasty on GERD.

Article Abstract

Purpose Of Review: Bariatric surgery and endoluminal bariatric therapies (EBTs) form an increasingly utilized therapeutic approach to treat obese patients but may worsen gastroesophageal reflux disease (GERD). In this updated article, we review the evidence on the effects of bariatric procedures on GERD.

Findings: Recent evidence implicates sleeve gastrectomy with the highest rates of de novo GERD and Barrett's esophagus (BE), whereas malabsorptive-restrictive procedures such as Roux-en-Y gastric bypass (RYGB) and one anastomosis gastric bypass (OAGB) were shown to have significantly lower reported rates. The intragastric balloon (IGB) has been associated with increased likelihood of GERD, whereas insufficient evidence exists linking endoscopic sleeve gastroplasty (ESG) to GERD.

Summary: Gastroesophageal reflux disease may be treated with some bariatric procedures but is often developed de novo as a result of the change in anatomy. Patients set to undergo bariatric surgery may benefit from pre-procedural endoscopy to choose the more suitable therapy. Further studies with objective measurements of GERD post procedure may provide more insight into the effects of bariatric therapies on reflux, especially more novel ones such as ESG.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11938-020-00278-yDOI Listing

Publication Analysis

Top Keywords

effects bariatric
12
bariatric surgery
12
bariatric therapies
12
gastroesophageal reflux
8
reflux disease
8
bariatric procedures
8
gastric bypass
8
bariatric
7
gerd
5
surgery endoscopic
4

Similar Publications

Background: Apart from massive weight loss, metabolic and bariatric surgery, especially gastric bypass (Roux-en-Y gastric bypass [RYGB]), can cause nutritional deficiencies. Proton pump inhibitors (PPI), relatively often used after RYGB, are associated with reduced calcium absorption. We have studied the long-term impact of PPI upon calcium homeostasis among RYGB patients.

View Article and Find Full Text PDF

Novel nutrition strategies in gastric and esophageal cancer.

Expert Rev Gastroenterol Hepatol

January 2025

Department of Surgery, Trinity St. James's Cancer Institute, Dublin, Ireland.

Introduction: Advances in treatment strategies for gastric and esophageal cancer have led to improved long-term outcomes, however the local and systemic effects of tumor growth, neoadjuvant therapies and surgery, results in specific nutritional challenges. Comprehensive nutritional evaluation and support represents a core component of multidisciplinary holistic care for this patient population.

Areas Covered: This review provides a detailed overview of the nutritional challenges in gastric and esophageal cancer, with a focus on malignant obstruction, preoperative optimization and nutrition in survivorship.

View Article and Find Full Text PDF

Background: Classic congenital adrenal hyperplasia, primarily due to 21-hydroxylase deficiency, leads to impaired cortisol and aldosterone production and excess adrenal androgens. Lifelong glucocorticoid therapy is required, often necessitating supraphysiological doses in youth to manage androgen excess and growth acceleration. These patients experience higher obesity rates, hypertension, and glucose metabolism issues, complicating long-term health management.

View Article and Find Full Text PDF

Maternal and neonatal outcomes after metabolic and bariatric surgery among women with severe obesity.

Surg Obes Relat Dis

January 2025

Department of Surgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York; Division of Health Services Policy and Practice, Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York.

Background: Earlier evidence indicated that metabolic and bariatric surgery (MBS) may adversely affect neonatal outcomes among patients conceiving soon after MBS, but recent studies demonstrated conflicting results, especially for new surgical techniques.

Objectives: The aim of this study was to assess the effects of MBS types and surgery to birth interval on maternal, birth, and nonbirth outcomes in women with severe obesity.

Setting: New York State's all-payer hospital discharge database (2008-2019).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!