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Adv Gerontol
January 2025
Saint-Petersburg Institute of Bioregulation and Gerontology, 3 Dynamo av., St. Petersburg 197119, Russian Federation, e-mail:
Adv Gerontol
January 2025
Samara State Medical University, 89 Chapayevskaya str., Samara 443099, Russian Federation, e-mail:
According to the federal register, up to 3,77 million elderly Russians have a confirmed diagnosis of type 2 diabetes mellitus (DM2), the most important criterion for the effectiveness of treatment of which is the achievement of therapeutic control targets. At the same time, the structure of the algorithm for their assessment in elderly patients is quite complex and involves the analysis of many different parameters, including indicators of geriatric status. The aim of the study was to develop a digital clinical calculator for determining individual goals of DM2 control in elderly patients based on the principles of evidence-based medicine.
View Article and Find Full Text PDFOpen Vet J
November 2024
Theriogenology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Background: Senility influences fertility in women and companion animals, especially horses.
Aim: This study aimed to investigate the effect of aging in horses on the daily changes in the dominant follicle (DF) dynamics and hemodynamics, antimüllerian hormone (AMH), enzymes, antioxidants, and ovarian hormones during the estrous cycle.
Methods: Ovaries of old mares ( = 5, age >20 years) and young native mares ( = 6, age <10 years) were scanned during 6 different estrous cycles from March 2022 to August 2023 with Doppler ultrasound.
Nutrients
November 2024
Department of Psychiatry and Behavioral Science, Kanazawa University Graduate School of Medical Sciences, Takara-machi 13-1, Kanazawa 920-8040, Japan.
Excessive consumption of vegetable oils such as soybean and canolla oils containing ω-6 polyunsaturated fatty acids is considered one of the most important epidemiological factors leading to the progression of lifestyle-related diseases. However, the underlying mechanism of vegetable-oil-induced organ damage is incompletely elucidated. Since proopiomelanocortin (POMC) neurons in the hypothalamus are related to the control of appetite and energy expenditure, their cell degeneration/death is crucial for the occurrence of obesity.
View Article and Find Full Text PDFExp Gerontol
December 2024
Health Management Center, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China. Electronic address:
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