In response to the 2013-2016 Ebola virus disease (EVD) outbreak primarily affecting Guinea, Sierra Leone, and Liberia, the World Health Organization (WHO) set out , which covered social distancing, research in outbreak settings, and clinical care. This article assesses the 's recommendations on research and long-term storage of biological specimens during infectious disease outbreaks and argues that the does not provide adequate direction for responders', researchers', and organizations' actions. It considers local persons' access to benefits of research in the aftermath of outbreaks and preparedness for outbreaks, drawing on lessons from both the 2013-2016 EVD outbreak and ongoing research in the Democratic Republic of the Congo.
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http://dx.doi.org/10.1001/amajethics.2020.28 | DOI Listing |
Infect Dis Poverty
January 2025
School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.
Background: Hemorrhagic fever with renal syndrome (HFRS) is a climate-sensitive zoonotic disease that poses a significant public health burden worldwide. While previous studies have established associations between meteorological factors and HFRS incidence, there remains a critical knowledge gap regarding the heterogeneity of these effects across diverse epidemic regions. Addressing this gap is essential for developing region-specific prevention and control strategies.
View Article and Find Full Text PDFBMC Vet Res
January 2025
Laboratory of Veterinary Infectious Disease, College of Veterinary of Medicine, Jeonbuk National University, Iksan, Jeonbuk, 54596, Republic of Korea.
Background: Akabane virus (AKAV) is an arthropod-borne virus that causes congenital malformations and neuropathology in cattle and sheep. In South Korea, AKAVs are classified into two main genogroups: K0505 and AKAV-7 strains. The K0505 strain infects pregnant cattle, leading to fetal abnormalities, while the AKAV-7 strain induces encephalomyelitis in post-natal cattle.
View Article and Find Full Text PDFJ Transl Med
January 2025
School of Medicine, Shanghai Baoshan Luodian Hospital, Shanghai University, Shanghai, 201908, China.
This review seeks to elucidate the therapeutic potential of tumor necrosis factor receptor 1 (TNFR1) and enhance our comprehension of its role in disease mechanisms. As a critical cell-surface receptor, TNFR1 regulates key signaling pathways, such as nuclear factor kappa-B (NF-κB) and mitogen-activated protein kinase (MAPK), which are associated with pro-inflammatory responses and cell death. The intricate regulatory mechanisms of TNFR1 signaling and its involvement in various diseases, including inflammatory disorders, infectious diseases, cancer, and metabolic syndromes, have attracted increasing scholarly attention.
View Article and Find Full Text PDFBMC Health Serv Res
January 2025
Health Systems Transformation Platform (HSTP), AISF Building, First Floor, Kalka Devi Marg, Lajpat Nagar IV, New Delhi, 110024, India.
Background: Multimorbidity is associated with significant out-of-pocket expenditures (OOPE) and catastrophic health expenditure (CHE), especially in low- and middle-income countries like India. Despite this, there is limited research on the financial burden of multimorbidity in outpatient and inpatient care, and cross-state comparisons of CHE are underexplored.
Methods: We conducted a cross-sectional analysis using nationally representative data from the National Sample Survey 75th Round 'Social Consumption in India: Health (2017-18)', focusing on patients aged 30 and above in outpatient and inpatient care in India.
BMC Public Health
January 2025
Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Dokuz Eylul University, İzmir, Türkiye.
Background: MPOX (Monkeypox) is a zoonotic disease of increasing global concern due to its re-emergence and potential for human-to-human transmission. Effective public health interventions rely on understanding socio-demographic determinants of knowledge and perceptions of the disease. This study aimed to investigate MPOX-related knowledge and concerns among a diverse sample in Türkiye, identifying key factors influencing knowledge levels.
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