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Single Dose of Doxycycline for the Prevention of Tick-borne Relapsing Fever. | LitMetric

AI Article Synopsis

  • The standard treatment for preventing tick-borne relapsing fever (TBRF) involves taking doxycycline for 5 days.
  • An observational study with 77 spelunkers, who are at high risk for TBRF, was conducted.
  • Results showed that a single 100 mg dose of doxycycline within 72 hours of tick exposure was completely effective in preventing TBRF.

Article Abstract

The current postexposure prophylaxis regimen for tick-borne relapsing fever (TBRF) consists of 5 days' doxycycline. In this observational study of 77 spelunkers at high risk for TBRF, a single dose of 100 mg doxycycline taken up to 72 hours after exposure to ticks was 100% effective in preventing the disease.

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Source
http://dx.doi.org/10.1093/cid/ciaa034DOI Listing

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