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Depsidones and diaryl ethers from potato endophytic fungus Boeremia exigua. | LitMetric

Depsidones and diaryl ethers from potato endophytic fungus Boeremia exigua.

Fitoterapia

School of Pharmacy, Anhui University of Chinese Medicine, Anhui Key Laboratory of Modern Chinese Materia Medica, Hefei 230012, People's Republic of China; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, People's Republic of China. Electronic address:

Published: March 2020

AI Article Synopsis

Article Abstract

Three depsidones boremexins A-C (1-3), two diaryl ethers boremexins D (4) and E (5), together with four known compounds were obtained from cultures of potato endophytic fungus Boeremia exigua. Their structures with absolute configurations were established by extensive spectroscopic methods and electronic circular dichroism (ECD) calculations. Compounds 1-4, 6, and 9 displayed anti-inflammatory properties on nitric oxide production in LPS-induced RAW264.7 macrophages with an IC range of 19.4-34.4 μM. Compounds 2 and 5 exhibited cytotoxicities to human breast cancer cell line (MCF-7) with IC values of 33.1 and 4.0 μM, respectively.

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Source
http://dx.doi.org/10.1016/j.fitote.2020.104483DOI Listing

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