Background: Cardiorenal syndrome (CRS) is a group of pathophysiological disorders affecting heart and kidneys.
Case Presentation: We present 44-year-old kidney transplant recipient with acute-on-chronic graft failure in the course of CRS due to acutely decompensated heart failure associated with severe aortic regurgitation successfully treated with aortic valve replacement. Because of graft failure progression and difficult to eradicate infections he was treated with dialysis and radical minimization of immunosuppression. After 74 days of renal replacement therapy the patient regained graft function after successful aortic valve replacement. The dialysis could be stopped and immunosuppressive therapy was reintroduced. Heart and renal function are stable and patient is doing well without dialysis for 3 years.
Conclusions: The return of kidney graft function can occur even after a long period of dialysis therapy due to improved cardiovascular function. Therefore, distinguishing an acute-on-chronic CRS subtype is mandatory to enable specific patient approach.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969413 | PMC |
| http://dx.doi.org/10.1186/s12872-020-01328-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Valvular Heart Disease Care in Pakistan: Impact of the Multidisciplinary Valve Heart Team.
JACC Adv
December 2024
Department of Interventional Cardiology& structural heart interventions, NICVD, Karachi, Pakistan.
Background: Patients with complex valvular heart disease (VHD) should be evaluated by a multidisciplinary heart team (HT). In low- and middle-income countries, referral practices are more variable, permitting any physician to refer patients directly to a cardiac surgeon without prior formal evaluation by a cardiologist with expertise in VHD.
Objectives: The goal of the study was to examine the demographics of VHD patients seen in a large heart valve center in a low- and middle-income country and to assess the impact of the multidisciplinary HT in patients referred for valve surgery.
Valvular Heart Disease: Geography Is Destiny!
JACC Adv
December 2024
Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Effect of chronic total occlusion of coronary arteries on cardiovascular outcomes in patients undergoing transcatheter aortic valve replacement: A systematic review and meta-analysis.
Int J Cardiol Cardiovasc Risk Prev
March 2025
Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Background: Transcatheter aortic valve replacement (TAVR) has significantly advanced the treatment of severe aortic stenosis (AS), particularly in elderly patients who often have coexisting coronary artery disease (CAD). Chronic total occlusion (CTO), a severe form of CAD, may negatively impact outcomes in TAVR patients, though data are limited. This meta-analysis aims to evaluate the impact of CTO on TAVR outcomes.
View Article and Find Full Text PDFFirst in Asia: Ventricular tachycardia ablation in patients with mechanical aortic and mitral valves using right atrium to left ventricle approach.
J Arrhythm
February 2025
Division of Cardiology, Department of Medicine, Heart Rhythm Center Taipei Veterans General Hospital Taipei Taiwan.
With the cases of mechanical valves, especially double mitral and aortic valves, ablation at the left ventricle is very challenging. This case report used equipments that are readily available in the Electrophysiology laboratory, which can make the access feasible.
View Article and Find Full Text PDFand coinfection in a patient with multiple myeloma: Case report.
Heliyon
January 2025
Lithuanian University of Health Sciences, Faculty of Medicine, A.Mickeviciaus street, 9, LT-44307, Kaunas, Lithuania.
Introduction: is a formidable pathogen that poses a significant threat to immunocompromised and might cause rare atypical forms of the disease especially complicated with coinfection.
Case: We present a case of a patient with meningoencephalitis, endocarditis, sepsis, and osteomyelitis, highlighting the complexities of managing disseminated polymicrobial infection. A 64-year-old female with multiple myeloma treated with chemotherapy presented with fever, altered mental status, nausea, and diarrhea to the emergency department.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!