LOS in The Dysbiotic Gut.

Cell Host Microbe

Gale and Ira Drukier Institute for Children's Health, Weill Cornell Medicine, New York City, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York City, NY, USA; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Medicine, New York City, NY, USA. Electronic address:

Published: January 2020

The neonatal gut microbiome undergoes dynamic changes in response to many nutritional and environmental variables. A recent study by Singer et al. in Nature Medicine elucidates several mechanisms to inhibit the expansion of gut-derived pathobionts in a dysbiotic neonatal gut and prevent these pathobionts from disseminating systemically and causing sepsis in neonatal mice.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050193PMC
http://dx.doi.org/10.1016/j.chom.2019.12.009DOI Listing

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