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A new alkynol compound from and its cytotoxicity. | LitMetric

A new alkynol compound from and its cytotoxicity.

Nat Prod Res

Department of Pathogen Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.

Published: October 2021

A new alkynol, platycodynol (), identified as 2, 3, 9, 13, 14-pentahydroxy-4, 6-tetradecadiyne, along with six known compounds () were obtained from for the first time. Their structures were elucidated with infrared (IR), ultraviolet (UV), 1D and 2D nuclear magnetic resonance (NMR) spectroscopic analysis as well as by high resolution electrospray ionization mass spectroscopy (HRESIMS). Platycodynol showed cytotoxicity against S180, A549 and SPC-A-1 cancer cells but no cytotoxicity against normal cells NCTC1469 and HL-7702 by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method.

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http://dx.doi.org/10.1080/14786419.2020.1712381DOI Listing

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