We describe a method for fabricating a three-dimensional hollow and elastic aneurysm model, which is useful for surgical clipping simulation. In this paper, we explain the generation of such hollow elastic model, based on 3D printing. Also, we report on the effects of applying it to presurgical clipping election and simulation. The advantages of this methodology are: (1) it generates a hollow and flexible 3D biomodel, represented as the vascular areas, apart from having together the skull, as a reference system; (2) it employs an inexpensive and easy to reproduce methodology; (3) it helps not only for training neurosurgeons, but also for planning and guiding the actual surgery clip's insertion.
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http://dx.doi.org/10.1109/EMBC.2019.8856514 | DOI Listing |
Food Res Int
February 2025
School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China. Electronic address:
Using Pickering emulsion (PE) as the carrier of active compounds in bio-based coatings constitutes a highly promising research domain. This study focused on creating a food-grade, biocompatible, and antibacterial PE to coat fresh fruits and vegetables, extending their shelf life. Hollow zein/soluble soybean polysaccharide nanoparticles loaded with thymol (H-ZSH/T) were produced using NaHCO as a sacrificial template to stabilize PE.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
College of Water Resources and Construction Engineering, Shihezi University, Shihezi 832000, China.
The collapse of surface goaf beneath highways can result in instability and damage to roadbeds. However, filling the goaf areas with foam concrete can significantly enhance the stability of the roadbeds while considerably reducing the costs of filling materials. This study analyzes the effects on destructive characteristics, mechanical properties, stress-strain curve features, and relevant metrics, while also observing the microstructure of basalt fiber-calcined gangue-silty clay foam concrete (BF-CCG-SCFC).
View Article and Find Full Text PDFMol Pharm
January 2025
School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Microneedles (MNs) offer the potential for discrete and painless transdermal drug delivery, yet poor insertion and dosing consistency have hindered their clinical translation. Specifically, hollow MNs are appropriate for the administration of liquid modalities, including insulin, which could prove to be beneficial for patients with type 1 diabetes mellitus. This work aimed to design and manufacture a hollow MN with an improved insertion and delivery profile suitable for insulin administration.
View Article and Find Full Text PDFSci Rep
November 2024
School of Civil Engineering, University of Science and Technology Liaoning, No. 189 Qianshan Middle Road, Lishan District, Anshan City, 114051, Liaoning Province, People's Republic of China.
Connection method of lengthening the steel tube of circular hollow sandwich concrete-filled steel tube by inside lining tube and thread is proposed. Twelve circular hollow sandwich concrete filled steel tubular beam-column connected by thread through inside lining tube are designed and fabricated using the length of the thread along the axial direction, the working height of the thread, and the position of the thread as parameters; In addition, one unconnected specimen and two welded specimens also are designed and fabricated to conduct controlled experimental research. The test phenomena and failure modes, axial compressive load-compression curve, axial compressive load-lateral deflection curve, and axial compressive load-strain in steel tube curve, as well as bearing capacity, strength reservation, deflection curve shape, lateral stiffness, ductility and plane section assumption are analyzed.
View Article and Find Full Text PDFComput Methods Programs Biomed
December 2024
Department of Mechanical and Aerospace Engineering, Polito(BIO)Med Lab, Politecnico di Torino, Corso Duca degli Abruzzi, 24, Torino, Turin 10129, Italy. Electronic address:
Background And Objectives: Vascular stents are scaffolding structures implanted in the vessels of patients with obstructive disease. Stents are typically designed as cylindrical lattice structures characterized by the periodic repetition of unit cells. Their design, including geometry and material characteristics, influences their mechanical performance and, consequently, the clinical outcomes.
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