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Antenatal screening - The roles of medical and family history, routine tests, and examination findings.
Best Pract Res Clin Obstet Gynaecol
December 2024
Department of Obstetrics & Gynaecology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong. Electronic address:
Routine antenatal care includes history, examination, and several standard laboratory tests. Other than the original objectives, the generated data is seldom utilised for screening for adverse obstetric and perinatal outcomes. Although new approaches and sophisticated tests improve prediction of complications such as pre-eclampsia, these may not be available globally.
View Article and Find Full Text PDFScreening for TORCH Antibodies in Croatian Childbearing-Aged Women, 2014-2023.
Antibodies (Basel)
June 2024
Department of Virology, Croatian Institute of Public Health, 10000 Zagreb, Croatia.
Article Synopsis
- - Detection and monitoring of TORCH infections during pregnancy is crucial, as they can lead to severe congenital abnormalities despite typically causing mild morbidity in mothers.
- - A study testing 1,032 women revealed varying seroprevalence rates for TORCH pathogens: 20.1% for toxoplasmosis, 91.3% for rubella, 70.5% for cytomegalovirus, 66.8% for HSV-1, and 3.5% for HSV-2, with age and geography influencing these rates.
- - There has been a declining trend in seroprevalence for TORCH pathogens compared to earlier studies (2005-2011), suggesting that monitoring maternal serology
Medium-term storage of frozen residual antenatal sera in gel separator tube is suitable for subsequent serological investigation of intrauterine infection.
J Clin Pathol
October 2024
Microbiology, Singapore General Hospital, Singapore.
Aim: We assessed the feasibility of storing sera in primary gel separator tube over medium-term for retrospective serological tests to facilitate investigation of intra-uterine infection.
Method: 120 residual serum samples, consisting of 30 positive samples each for rubella, cytomegalovirus, parvovirus B19 and varicella zoster IgG were aliquoted into secondary propylene tubes and stored together with the original primary tubes at -20°C for 1 year. The serum was subsequently retested to compare results from both storage methods.
Seroprevalence and risk factors for rubella infection in pregnant women attending a tertiary hospital in Kano-Nigeria.
Pan Afr Med J
February 2024
Department of Obstetrics and Gynaecology, Bayero University, Kano, Nigeria.
Introduction: rubella is a leading cause of vaccine preventable birth defects especially in developing countries. Acquisition of infection with the rubella virus in early pregnancy exposes the fetus to a very high chance of developing congenital rubella syndrome. The neonate is born with multiple abnormalities with the triad of congenital cataract, deafness and cardiovascular abnormalities like ventricular septal defect or patent ductus arteriosus.
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