We developed a new 2.5 μm global shutter (GS) pixel using a 65 nm process with an advanced light pipe (LP) structure. This is the world's smallest charge domain GS pixel reported so far. This new developed pixel platform is a key enabler for ultra-high resolution sensors, industrial cameras with wide aperture lenses, and low form factors optical modules for mobile applications. The 2.5 μm GS pixel showed excellent optical performances: 68% quantum efficiency (QE) at 530 nm, ±12.5 degrees angular response (AR), and quite low parasitic light sensitivity (PLS)-10,400 1/PLS with the F#2.8 lens. In addition, we achieved an extremely low memory node (MN) dark current 13 e/s at 60 °C by fully pinned MN. Furthermore, we studied how the LP technology contributes to the improvement of the modulation transfer function (MTF) in near infrared (NIR) enhanced GS pixel. The 2.8 μm GS pixel using a p-substrate showed 109 lp/mm MTF@50% at 940 nm, which is 1.6 times better than that without an LP. The MTF can be more enhanced by the combination of the LP and the deep photodiode (PD) electrically isolated from the substrate. We demonstrated the advantage of using LP technology and our advanced stacked deep photodiode (SDP) technology together. This unique combination showed an improvement of more than 100% in NIR QE while maintaining an MTF that is close to the theoretical Nyquist limit (MTF @50% = 156 lp/mm).
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http://dx.doi.org/10.3390/s20010307 | DOI Listing |
ChemSusChem
January 2025
IIT Bombay, Dept of Metallurgical Engineering and Materials Science, IIT Bombay, 400076, Mumbai, INDIA.
Multi-domain biological and environmental research highlights the efficacy of carbon quantum dots (CQDs) as asafer alternative to toxic metal-based quantum dots (QDs) and expensive conventional organic dyes, particularly in biomedical applications. CQDs are often functionalized by metal heteroatoms to improve their electron-donating properties and modify charge density, thereby enhancingtheir physicochemical characteristics. However, metal doping may re-introduce toxicity concerns as in traditional QDs and further increase environmental risks.
View Article and Find Full Text PDFJACS Au
January 2025
Department of Physics, Freie Universität Berlin, Arnimallee 14, Berlin 14195, Germany.
Interactions of polyelectrolytes (PEs) with proteins play a crucial role in numerous biological processes, such as the internalization of virus particles into host cells. Although docking, machine learning methods, and molecular dynamics (MD) simulations are utilized to estimate binding poses and binding free energies of small-molecule drugs to proteins, quantitative prediction of the binding thermodynamics of PE-based drugs presents a significant obstacle in computer-aided drug design. This is due to the sluggish dynamics of PEs caused by their size and strong charge-charge correlations.
View Article and Find Full Text PDFJACS Au
January 2025
Department of Cell and Molecular Biology, Uppsala University, 751 24 Uppsala, Sweden.
Disordered regions are an important functional feature of many multidomain proteins. A prime example is proteins in membraneless organelles, which contain folded domains that engage in specific interactions and disordered low-complexity (LC) domains that mediate liquid-liquid phase separation. Studying these complex architectures remains challenging due to their conformational variability.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06536, USA.
To regain infectivity, Trypanosoma brucei, the pathogen causing Human and Animal African trypanosomiasis, undergoes a complex developmental program within the tsetse fly known as metacyclogenesis. RNA-binding protein 6 (RBP6) is a potent orchestrator of this process, however, an understanding of its functionally important domains and their mutational constraints is lacking. Here, we perform deep mutational scanning of the entire RBP6 primary structure.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Department of Materials Science and Engineering, Beijing Technology and Business University, Beijing 100048, PR China.
Achieving dual functionalities of hydrophobicity and excellent microwave transmission in a single material remains a significant challenge, especially for advanced applications in aerospace, telecommunications, and navigation engineering. Inspired by natural designs like chestnut burrs, bioinspired polyaniline (PANI) particles with tunable micro-/nanostructures through a facile template-free polymerization process have been developed. By regulating the polarity of the reaction system, temperature, and reaction time, various hierarchical structures, including cross-linked nanosheets, chestnut burr-like spheres, and starburst flower-like structures, are synthesized.
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