AI Article Synopsis

  • A study looked at how psilocybin, a substance found in magic mushrooms, affects anxiety and depression when combined with behavioral therapies.
  • The results showed that people who took psilocybin had big improvements in their anxiety and depression symptoms, with lots of data supporting it.
  • There weren't any serious side effects, but the researchers mentioned that there weren't many studies and some could have bias, so more research is needed.

Article Abstract

The current meta-analysis examined the effects of psilocybin in combination with behavioral interventions on anxiety and depression in samples with elevated symptoms. Across four studies (one uncontrolled; three randomized, placebo-controlled; N = 117), within-group pre-post and pre-follow-up effects on anxiety and depression were large (Hedges' gs=1.16 to 1.47) and statistically significant. Across three placebo-controlled studies, pre-post placebo-controlled effects were also large (gs = 0.82 to 0.83) and statistically significant. No serious adverse events were reported. Limitations include the small number of studies and risk for bias within studies. Results tentatively support future research on psilocybin for the treatment of anxiety and depression.

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Source
http://dx.doi.org/10.1016/j.psychres.2020.112749DOI Listing

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