Genetic twin studies may shed light on the genetic basis as well as environmental and epigenetic factors in disease pathogenesis. Herein, we present four pairs of monozygotic twins sharing similar phenotypes in three dermatologic conditions, and a literature review regarding twin studies in these diseases.
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Report of the 19th International Congress on Twin Studies, 26-28 September 2024, Assisi, Italy.
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Medical Imaging Centre, Semmelweis University, Budapest, Hungary.
The International Society for Twin Studies (ISTS) held its 19th scientific congress in Assisi, Italy, from September 26 to 28, 2024. This prestigious event, which was the seventh joint meeting with the World Congress on Twin Pregnancy, brought together researchers from various fields, including psychology, biology and medicine. Representatives from ICOMBO (the International Consortium of Multiple Birth Organisations), which supports multiple-birth families worldwide, were also in attendance.
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Centre for Psychology and Evolution, School of Psychology, University of Queensland, Queensland, Australia.
Thanks to twin studies, it has been known for decades that human same-sex sexual behavior (SSB) has a substantial heritable component. However, only recently have large genome-wide association studies (GWAS) begun to illuminate the complex genetics involved. These studies have established that SSB is influenced by many common genetic variants, each with tiny but cumulative effects.
View Article and Find Full Text PDFUnraveling Mechanisms of Genetic Risks in Metabolic Dysfunction-Associated Steatotic Liver Diseases: A Pathway to Precision Medicine.
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MASLD Research Center, Division of Gastroenterology, University of California at San Diego, La Jolla, California, USA; email:
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health problem, affecting ∼1 billion people. This condition is well established to have a heritable component with strong familial clustering. With the extraordinary breakthroughs in genetic research techniques coupled with their application to large-scale biobanks, the field of genetics in MASLD has expanded rapidly.
View Article and Find Full Text PDFTwin testosterone transfer hypothesis and the second-to-fourth digit ratio in females of same-sex and opposite-sex twin pairs: An exploratory study.
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Department of Epidemiology, Biostatistics and Disease Control, University for Development Studies, Tamale, Ghana.
The twin testosterone transfer (TTT) hypothesis posits that females with male co-twins (opposite-sex, OS) might develop male-typical traits due to higher prenatal testosterone exposure. This study explored whether females of OS have lower 2D:4D digit ratios and higher testosterone levels compared to females of same-sex (SS) twin pairs. Conducted in Tamale from January to December 2022, the study included 40 participants aged 18-27 years: 10 males of OS, 10 females of OS, and 20 females of SS twin pairs.
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J Transl Med
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Department of Epidemiology and Health Statistics, The School of Public Health of Qingdao University, 308 Ningxia Road, Qingdao, 266071, Shandong, People's Republic of China.
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