HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation.

Chem Commun (Camb)

Department of Chemistry and Biochemistry, University of Missouri - St. Louis, One University Boulevard, St. Louis, Missouri 63121, USA.

Published: January 2020

Reported herein is the development of a user-friendly platform for simple and transformative automation based on standard HPLC equipment. We showcase how the improved platform works in application to the completely automated, a "press of the button," synthesis of various glycan sequences.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656230PMC
http://dx.doi.org/10.1039/c9cc08876hDOI Listing

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