AI Article Synopsis
- The text discusses the significance of a specific fungal complex in causing dermatophytosis, highlighting that proper identification of its species is crucial for effective treatment due to varying antifungal susceptibilities.
- A study characterized 55 fungal isolates from patients in Yucatán, Mexico, using both morphological analysis on Sabouraud dextrose agar and molecular sequencing of specific DNA regions.
- The results indicated that all isolates belonged to the same complex, with different colony textures categorized as powdery or velvety, reflecting various underlying infections in the patients.
Article Abstract
The complex is the second most common causal agent of dermatophytosis. It comprises five species-, , , and as well as nine different genotypes of / -which are morphologically similar; however, their susceptibility to antifungal agents may differ. For targeted therapy and better prognosis, it is important to identify these species at a molecular level. However, since many hospitals lack molecular methods, the actual aetiology of dermatophytosis caused by this complex remains unknown. To characterize 55 anthropophilic isolates of the complex recovered from a dermatological centre in Yucatán, Mexico. Fifty-five isolates of the complex were obtained from patients with , , , , and . They were characterized by their colonial and microscopic morphology on Sabouraud dextrose agar (SDA) and through the sequencing of a fragment from the region ITS1-5.8S-ITS2. All colonies grown on SDA were white. Forty-six isolates formed colonies with a powdery texture, while nine isolates formed colonies with a velvety texture. The micromorphological features were typical of the complex. The molecular analysis revealed that 55 isolates were microorganisms that belonged to the complex, that 46 formed powdery colonies representing , and that the other nine isolates that formed velvety colonies represented . The latter nine isolates were obtained from patients with , , and . The colony morphology on SDA led to the identification of 46 isolates as and nine isolates as . At a molecular level, the species identified by their morphology were identified only as complex.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945559 | PMC |
| http://dx.doi.org/10.7150/ijms.35173 | DOI Listing |
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