New compounds from the aerial parts of Burm.f. and their antioxidant and anti-inflammatory activities.

Nat Prod Res

Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, China.

Published: October 2021

Three new compounds (-), together with six known compounds (-), were isolated from the ethyl acetate fraction of ethanol extract of the aerial parts of Burm.f. All of these known compounds were isolated from the plant for the first time. Their structures including absolute configurations were elucidated on the basis of HR-ESI-MS, NMR spectroscopic analyses, single crystal X-ray diffraction and comparison with the literatures. Compounds - were tested for their antioxidant and anti-inflammatory activities. Compounds and showed the antioxidant activities with IC values of 28.61 ± 1.56 and 22.55 ± 1.38 M, respectively. Compounds and showed anti-inflammatory activity in LPS-induced RAW 264.7 macrophages with the IC values of 20.95 ± 1.11 and 16.50 ± 1.04 M, respectively.

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http://dx.doi.org/10.1080/14786419.2019.1710708DOI Listing

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