Objectives: Pasteurella bacteraemia is rare, but has been associated with a high mortality rate. The aim of this study was to estimate the impact of comorbidities on patients with Pasteurella bacteraemia.
Methods: All cases of Pasteurella bacteraemia in adults treated in our centre between January 2008 and December 2017 were included retrospectively and compared with cases identified in a systematic review of the literature via MEDLINE covering the years 1951-2017. The epidemiological, bacteriological, and clinical data were collected, as well as the instances of death after 30 days.
Results: Twenty cases of Pasteurella bacteraemia identified in our centre and 99 cases from the literature review were included. A major comorbidity was found in 80/119 (67.2%) patients. The death rate at 30 days was 31.1%. The most common comorbidities were cirrhosis, immunosuppressive therapy, and malignant diseases. Age was not associated with mortality. On multivariate analysis, the only factor associated with mortality was a major comorbidity (odds ratio 2.78, 95% confidence interval 1.01-7.70; p = 0.04).
Conclusions: This study confirms the high mortality rate and highlights the importance of the host background, independent of age, in Pasteurella bacteraemia. Clinicians should be aware of the comorbidities in cases of Pasteurella infection, due to the poor prognosis of bacteraemia.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijid.2020.01.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of a MALDI-TOF MS model for differentiating haemorrhagic septicaemia-causing strains of Pasteurella multocida from other capsular groups.
J Microbiol Methods
December 2024
Nebraska Veterinary Diagnostic Center, School of Veterinary Medicine and Biomedical Sciences, Institute of Agriculture and Natural Resources, University of Nebraska-Lincoln, Lincoln, NE, USA.
Pasteurella multocida capsular types A, D, and F cause disease in many animal hosts, including bovine respiratory disease in cattle, which is one of the most globally significant animal diseases. Additionally, P. multocida capsular types B and E cause haemorrhagic septicaemia, a devastating disease primarily of cattle, water buffalo, and bison that develops rapidly with high mortality.
View Article and Find Full Text PDFThe first report of concurrent infection of hemorrhagic septicemia with foot and mouth disease in cattle in Bangladesh.
Comp Immunol Microbiol Infect Dis
December 2024
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh. Electronic address:
This study aimed to investigate the concurrent infection of Pasteurella multocida (P. multocida) type B:2, which causes Hemorrhagic Septicemia (HS), with cases of Foot and Mouth Disease (FMD) outbreaks in cattle in Bangladesh between March and December 2023. Samples were collected from 11 distinct outbreak areas, totaling 102 samples.
View Article and Find Full Text PDFA Case of Persistent Pasteurella multocida Cellulitis Complicated With Large Endocarditis Vegetation.
Cureus
September 2024
Infectious Disease, Cleveland Clinic Akron General, Akron, USA.
Article Synopsis
- There’s a rare bacteria that can infect heart valves, usually found in the mouths of pets like cats and dogs, and it can cause serious infections in humans, especially after bites or scratches.
- A 73-year-old woman with liver problems got very sick after recently having a skin infection and hospital stay, showing symptoms like weakness and fever.
- Doctors found a dangerous mass on her heart valve but couldn’t do surgery, so they treated her with strong antibiotics, which eventually helped her get better before she went home.
Pasteurella spp. can cause fatal zoonotic infections in humans. We performed a multicenter study to investigate the prevalence and clinical features of Pasteurella infections in South Korea during 2018‒2022.
View Article and Find Full Text PDFExploring the intricacies of Pasteurella multocida dynamics in high-altitude livestock and its consequences for bovine health: A personal exploration of the yak paradox.
Microb Pathog
September 2024
College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, PR China. Electronic address:
Pasturella multocida (P. multocida), a gram-negative bacterium, has long been a focus of interest in animal health because of its capacity to cause different infections, including hemorrhagic septicemia. Yaks, primarily found in high-altitude environments, are among the several livestock animals affected by these bacteria.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!