[Flowmetrical features of the postoperative wound process in drug addicted patients with chronic odontogenic osteomyelitis of the jaws when using different surgical approaches].

The aim of the work was to study changes in local microhemodynamic indices in drug addicted patients in the course of the treatment of chronic odontogenic osteomyelitis. Assessment of tissue blood flow in gingival mucosa in patients with chronic osteomyelitis was performed using Laser doppler flowmetry. All patients were divided into two groups, namely treatment (n=21) and control (n=19). Sequestrectomy was performed to the patients from the treatment group with a bone defect closed with a concomitant use of PRP gel and FRP membranes. The same surgery was performed to patients from control group with a bone defect closed with iodoform tampon. During the study it was revealed that sequestrectomy with use of PRP gel and FRP membranes leads to rapid decrease in local postoperative inflammatory reactions, improvement of venous outflow and better functioning of microvessels endothelium and general optimization of the tissue healing process in drug addicted patients with chronic odontogenic osteomyelitis.