Objective: To report the long-term outcome of horses treated with interspinous ligament desmotomy (ISLD) for pain associated with overriding dorsal spinous processes (ORDSP) and determine the influence of preoperative diagnostic analgesia on long-term outcome.
Study Design: Retrospective study.
Animals: Eighteen horses.
Methods: Data were collected from horses presenting for ISLD to the University of Pennsylvania New Bolton Center between January 2013 and May 2018. Follow-up of ≥3 months postsurgically was obtained from the owner, trainer, or referring veterinarian. Long-term improvement was compared between horses that improved with diagnostic analgesia presurgically and horses that did not undergo diagnostic analgesia presurgically by using a χ test. Univariate logistic regression was used to test associations between long-term improvement and independent variables.
Results: Clinical signs had improved in 13 of 18 horses at long-term follow-up (median, 14.5 months; range, 3-57). Clinical signs improved in nine of 10 horses responding to diagnostic analgesia but only in four of eight horses that did not undergo diagnostic analgesia (χ [1], N = 18) = 3.55; P = .06). Although the likelihood of long-term improvement increased with prior diagnostic analgesia (odds ratio = 6.3; 95% confidence interval = 0.73, 55.0; P = .09), it did not reach statistical significance.
Conclusion: A higher proportion of horses experienced long-term improvement in clinical signs after ISLD when horses responding to preoperative diagnostic analgesia were compared with horses that were not tested.
Clinical Significance: This study provides some evidence to support the use of diagnostic analgesia in conjunction with clinical examination for identification of clinically relevant ORDSP.
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http://dx.doi.org/10.1111/vsu.13377 | DOI Listing |
J Indian Soc Pedod Prev Dent
October 2024
Department of Paediatric and Preventive Dentistry, ACPM Dental College, Dhule, Maharashtra, India.
Background: Audio-analgesia is one of the unexplored aspects of behavior management in pediatric dentistry, and recently, there have been many new inclusions in shades of noise that were previously just limited to white noise, like brown noise and pink noise.
Aim: The aim of the study was to evaluate and compare the effectiveness of white noise, brown noise, and pink noise on dental anxiety in pediatric patients undergoing primary tooth extraction.
Study Settings And Design: Multiarm, triple-blinded, parallel-group randomized controlled trial.
Vet Med Sci
January 2025
Department of Surgery, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkey.
Objective: To compare the impacts of Elizabethan collar (EC) and wound protection corset (WPC) on pain and discomfort levels in cats following ovariohysterectomy.
Study Design: Prospective, randomized controlled clinical trial.
Animals: Twenty-six healthy female cats.
Eur J Obstet Gynecol Reprod Biol
January 2025
Discipline of Surgery, University of Galway, Galway, Ireland.
Background: Outpatient hysteroscopy (OPH) is an important diagnostic and therapeutic intervention in gynaecology. However, the most common reason for failure is pain. Currently, there is no consensus regarding analgesia for OPH amongst the literature.
View Article and Find Full Text PDFElife
January 2025
Department of Neurosurgery, Washington University School of Medicine, Springfield, United States.
Background: Subarachnoid hemorrhage (SAH) is characterized by intense central inflammation, leading to substantial post-hemorrhagic complications such as vasospasm and delayed cerebral ischemia. Given the anti-inflammatory effect of transcutaneous auricular vagus nerve stimulation (taVNS) and its ability to promote brain plasticity, taVNS has emerged as a promising therapeutic option for SAH patients. However, the effects of taVNS on cardiovascular dynamics in critically ill patients, like those with SAH, have not yet been investigated.
View Article and Find Full Text PDFPsychophysiology
January 2025
Biological Psychology Lab, Department of Psychology, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
Transcutaneous vagus nerve stimulation (tVNS) offers a non-invasive method to enhance noradrenergic neurotransmission in the human brain, thereby increasing cognitive control. Here, we investigate if changes in cognitive control induced by tVNS are mediated through locus coeruleus-induced modifications of neural activity in the anterior cingulate cortex. Young healthy participants engaged in a simple cognitive control task focusing on response inhibition and a more complex task that involved both response inhibition and working memory, inside a magnetic resonance imaging scanner.
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