The frequency of clinically relevant transmitted drug resistance mutations (DRMs) against drugs used for 2-drug regimens was 15.6%, but only 2% were not eligible for 1 or more 2-drug regimens. More than 50% of patients harboring any clinically relevant DRMs were found to be part of genetic transmission clusters.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942491PMC
http://dx.doi.org/10.1093/ofid/ofz535DOI Listing

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