Background: The global burden of road injuries is known to follow complex geographical, temporal and demographic patterns. While health loss from road injuries is a major topic of global importance, there has been no recent comprehensive assessment that includes estimates for every age group, sex and country over recent years.
Methods: We used results from the Global Burden of Disease (GBD) 2017 study to report incidence, prevalence, years lived with disability, deaths, years of life lost and disability-adjusted life years for all locations in the GBD 2017 hierarchy from 1990 to 2017 for road injuries. Second, we measured mortality-to-incidence ratios by location. Third, we assessed the distribution of the natures of injury (eg, traumatic brain injury) that result from each road injury.
Results: Globally, 1 243 068 (95% uncertainty interval 1 191 889 to 1 276 940) people died from road injuries in 2017 out of 54 192 330 (47 381 583 to 61 645 891) new cases of road injuries. Age-standardised incidence rates of road injuries increased between 1990 and 2017, while mortality rates decreased. Regionally, age-standardised mortality rates decreased in all but two regions, South Asia and Southern Latin America, where rates did not change significantly. Nine of 21 GBD regions experienced significant increases in age-standardised incidence rates, while 10 experienced significant decreases and two experienced no significant change.
Conclusions: While road injury mortality has improved in recent decades, there are worsening rates of incidence and significant geographical heterogeneity. These findings indicate that more research is needed to better understand how road injuries can be prevented.
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http://dx.doi.org/10.1136/injuryprev-2019-043302 | DOI Listing |
Traffic Inj Prev
January 2025
School of Traffic & Transportation Engineering, Changsha University of Science & Technology, Changsha, Hunan, China.
Objective: This study aims to investigate the causes of 2-vehicle collisions involving an autonomous vehicle (AV) and a conventional vehicle (CV). Prior research has primarily focused on the causes of crashes from the perspective of AVs, often neglecting the interactions with CVs.
Method: To address this limitation, the study proposes a classification framework for crash causation patterns in 2-vehicle collisions involving an AV and a CV, considering their interactions.
Aust J Rural Health
February 2025
Doctoral Diploma of Medicine, Newcastle University, Callaghan, New South Wales, Australia.
Introduction: Research suggests a significant disparity between rural and urban trauma patient outcomes, causing substantial social, economic and emotional costs, impacting health-related quality of life and functionality, and straining our healthcare system. There has not been a systematic examination of contributing factors in Australia.
Objective: This study aims to systematically describe the nature of research on trauma outcomes by geographical location and (where possible) describe factors found to increase or decrease the likelihood and severity of injury in rural Australia.
J Mol Cell Cardiol Plus
September 2024
O'Brien Institute Department, St Vincent's Institute of Medical Research, Victoria 3065, Australia.
Dynamin-related protein 1 (Drp1) is a mitochondrial fission protein and a viable target for cardioprotection against myocardial ischaemia-reperfusion injury. Here, we reported a novel Drp1 inhibitor (DRP1i1), delivered using a cardiac-targeted nanoparticle drug delivery system, as a more effective approach for achieving acute cardioprotection. DRP1i1 was encapsulated in cubosome nanoparticles with conjugated cardiac-homing peptides (NanoDRP1i1) and the encapsulation efficiency was 99.
View Article and Find Full Text PDFCureus
December 2024
Emergency Medicine, West Midlands Deanery, Birmingham, GBR.
Cervical spine injuries are one of the most common injuries of the spine that are encountered in the emergency department (ED). More than half of all spinal injuries presenting to the ED involve the cervical spine, with nearly half of them resulting from road traffic accidents. The majority of spinal cord injuries are found to occur in males of younger age groups, with almost half of them resulting in incomplete spinal cord injuries.
View Article and Find Full Text PDFCureus
December 2024
Emergency Medicine Department, Aga Khan University, Karachi, PAK.
Background: Road traffic injuries (RTIs) are currently the ninth most common cause of mortality and are expected to increase in the future. RTIs rank in the top three reasons why young people die. Because of the high incidence and mortality risk, proper trauma care has been prioritized for RTI patients who present to the emergency department.
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