Background: Cerebral palsy (CP) is a common disability in children featured with pathological gait and limb function limitation due to muscle weakness. Improving limb function and quality of life is currently considered to be highlighted. Physiotherapy is a chief component of rehabilitation for children with CP, correcting gait and improve walking capacity through muscle strength training. Standard rehabilitation programs for CP have not been determined. Core stability training (CST), which coordinates limb balance via trunk control, is widely used in sports competition. And it is gradually introduced into the rehabilitation of children with cerebral palsy with a positive impact on the patients' gait performance. By screening published literatures, this study aims to conduct a meta-analysis to systematically evaluate the effectiveness and safety of CST in gait of children with CP.
Methods: Randomized controlled trials (RCTs) and controlled clinical trials (CCTs) on CST in the treatment of children with CP were searched from 6 databases. Moreover, the reference lists of conference papers and included literatures will be manually searched to avoid omissions. Literature screening and data extraction were performed independently by 2 researchers. RCTs carry out the risk of bias analysis evaluation from seven aspects through the Cochrane Collaboration's risk of bias tool. Fixed or random effect model will be performed to analyze the outcomes. When higher heterogeneity occurs (I > 50%), the sensitivity or subgroup analysis will also be conducted to find potential factors. And the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach is used for assessing the quality of evidence.
Results: The study will evaluate the effect of CST on gait of children with CP from multiple outcomes, including walking speed, endurance, stride length, and safety.
Conclusion: Based on evidence-based medicine, the conclusion of this study can demonstrate the effectiveness and safety of CST in gait correction for children with CP.
Prospero Registration Number: PROSPERO CRD 42019134094.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959942 | PMC |
http://dx.doi.org/10.1097/MD.0000000000018609 | DOI Listing |
Cerebellum
January 2025
Department of Neurology, Division of Neuro-Visual & Vestibular Disorders, The Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 N. Wolfe Street, Baltimore, MD, USA.
A 50-year-old woman with a 20-year history of gait instability presented with new-onset vertigo and oscillopsia. Examination revealed bilateral vestibular loss, cerebellar ataxia, sensory neuropathy, a "yes-yes" head tremor, nystagmus and a family history of a similar syndrome. Genetic testing for cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome (RFC1) was negative, but whole exome sequencing identified a novel mutation in the DNA methyltransferase 1 (DNMT1) gene, broadening the differential diagnosis for this phenotype.
View Article and Find Full Text PDFGait Posture
December 2024
Marquette University, 1250 W. Wisconsin Ave, Milwaukee, WI 53233, United States; Shriners Children's Chicago, 2211 N. Oak Park Ave, Chicago, IL 60707, United States.
Background: Understanding midfoot joint kinetics is valuable for improved treatment of foot pathologies. Segmental foot kinetics cannot currently be obtained in a standard gait lab without the use of multiple force plates or a pedobarographic plate overlaid with a force plate due to the single ground reaction force (GRF) vector.
Research Question: Can an algorithm be created to distribute the GRF into multiple segmental vectors that will allow for calculation of accurate midfoot and ankle moments?
Methods: 20 pediatric subjects (10 typically developing, 10 with foot pathology) underwent multi-segment foot gait analysis using the Milwaukee Foot Model.
Cureus
December 2024
Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.
Cerebral palsy (CP) is a group of neurological disorders that affect movement, muscle tone, and motor skills. Here, we present a case of an 11-year-old female patient who presented with tightness in both lower limbs, since birth, and delayed walking, accompanied by difficulty walking due to spasticity. She was diagnosed with spastic diplegic cerebral palsy.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
January 2025
Department of Neuroradiology (E.L.F., M.M.M., K.S.K.), Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona
Background And Purpose: Normal pressure hydrocephalus (NPH) is a diagnostic challenge because its clinical symptoms and imaging appearance resemble normal aging and other forms of dementia. Identifying NPH is essential so that patients can receive timely treatment to improve gait distortion and quality of life. An automated marker of NPH was developed and evaluated on clinical CT images, and its utility was assessed in a large patient cohort.
View Article and Find Full Text PDFPurpose: To examine associations between clinical measures (self-reported and clinician-administered) and subsequent injury rates in the year after concussion return to play (RTP) among adolescent athletes.
Methods: We performed a prospective, longitudinal study of adolescents ages 13-18 years. Each participant was initially assessed within 21 days of concussion and again within 5 days of receiving RTP clearance from their physician.
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