The ability of a single-sensor gas diagnosis device (SSGDD) as a virtual sensor array data to appraise thyme essential oils (TEO) based on its quantitatively release rate from nanofibres was aimed. To form nylon 6 fragrant electrospun nanofibre, TEO was added as a natural antibacterial substance under homogeniser to make a stable emulsion. The optimised nanofibre inactivated against Escherichia Coli and Staphylococcus Aureus bacteria up to >75% at once and to > 41.9% over 2-weeks period. Moreover, large differences in sensor responses to samples with experimental variables (percent TEO and storage time) and different odour intensity exist which correctly classified by discriminant function analysis. Odour intensity as an accessible incubator evinces the nanofibres efficiency which correlated to the antibacterial activity. With applying SSGDD technique as a quantified subjective solution, carefully odour assessment is possible and prepared mats could be demonstrated as a face-masks' promising candidate.
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http://dx.doi.org/10.1080/02652048.2020.1713241 | DOI Listing |
Sci Rep
January 2025
Research Assistant, Department of Prosthodontics, Faculty of Dentistry, University of Abant İzzet Baysal, Bolu, Turkey.
This study investigated denture care attitudes, dental visit habits, oral mucosal lesions, and hygiene levels in 118 complete denture users treated at a university dentistry faculty. Data on demographics, smoking, denture use duration, dentist visits, and hygiene habits were collected via a questionnaire. A specialist examined mucosal lesions and assessed denture hygiene level using the Budtz-Jorgensen and Bertram method.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
Background: Olfactory deficits are predictive of cognitive decline and dementia. Previous studies have linked brain magnetic resonance imaging markers of neurodegeneration to olfactory deficits in aging; however, these studies analyzed cross‐sectional data for markers, olfaction, or both. Furthermore, potential cerebrovascular contributions to understanding why olfactory deficits predict dementia remain unexplored.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Columbia University Irving Medical Center, New York, NY, USA
Background: Inexpensive, non‐invasive tests may improve the identification of persons at increased risk for cognitive decline and dementia. We compared impairment in odor identification and global cognition with neuro‐imaging biomarkers to predict cognitive decline and dementia in the population‐based Mayo Clinic Study of Aging (MCSA).
Method: At the 2008 assessment, 647 participants who were ≥ 55 years old with at least one follow‐up had the following procedures: modified Blessed Information‐Memory‐Concentration Test (BIMCT), 12‐item Brief Smell Identification Test (BSIT), brain magnetic resonance imaging (MRI), and Positron Emission Tomography (PET) amyloid imaging with 11C‐Pittsburgh compound B (11C‐PiB).
Alzheimers Dement
December 2024
Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Background: Few population‐based studies have comprehensively examined the association between impaired olfactory identification and the prevalence of mild cognitive impairment (MCI) and regional brain volumes in a general older population without dementia.
Method: A total of 1,292 participants without dementia aged 65 years or older underwent a Japanese Pocket Smell Test, an assessment of cognitive function, and a brain magnetic resonance imaging scanning in 2017‐2018. Impaired olfactory identification was defined as incorrect identification of three or more odors in the Japanese Pocket Smell Test, where participants sniffed eight microencapsulated odors (strawberries, chocolate, mint, smoke, soap, grapes, onions, and roses) and selected the corresponding odor from four choices for each odor.
Alzheimers Dement
December 2024
Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
Background: Olfactory impairment has been observed as an early sensory marker of cognitive decline and dementia, but its association with biomarkers of Alzheimer’s disease (AD) pathology remains understudied, particularly in the context of blood‐based biomarkers.
Method: Here, we examine six common biomarkers of AD, tau phosphorylated at threonine 181 (P‐tau181), total tau (T‐tau), amyloid‐β ratio (Aβ42/Aβ40), P‐tau181/Aβ42 ratio, neurofilament light (Nfl), and glial fibrillary acidic protein (GFAP), derived from serum at the baseline assessment of the population‐based Swedish National Study on Aging and Care in Kungsholmen (SNAC‐K; n = 1933, mean age at baseline = 71 years). Participants were free from dementia and neurodegenerative disorders at baseline.
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