AI Article Synopsis
- Gender compatibility between kidney donors and recipients significantly influences transplant success, with male donor to male recipient pairs showing the highest success rates.
- A study of 1113 kidney transplant recipients highlighted that factors like serum creatinine levels, eGFR, and donor hemoglobin are crucial for female recipients' outcomes, while history of dialysis remains a concern.
- The research recommends gender matching for optimal kidney transplant results, indicating that male to female transplants can be successful only under specific conditions, while female to male transplants are generally not advisable, particularly for older patients with a dialysis history.
Article Abstract
Background: Several factors such as recipient age, BMI, serum cratinine, and positive history of dialysis are important in predicting graft survival among kidney transplant recipients. One factor affecting the transplant outcomes is donors and recipients gender, which is usually ignored.
Methods: A total of 1113 kidney transplant recipients were studied in this retrospective cohort study. Several factors were taken into account for graft survival and outcomes such as donors and recipients gender and age in addition to common recipient factors like cratinine, eGFR, BMI, and positive history of dialysis.
Results: The most successful transplant based on donor-recipient gender was observed in male donor to male recipient, and then male donor to female recipient. In female transplant recipients, level of serum cratinine and eGFR, positive dialysis history before transplant, and low donor hemoglobin level can be considered as good prognostic factors recommended for kidney transplant survival.
Conclusions: Our results suggested gender matching for kidney transplant. Only in some exceptional conditions, male donor to female recipient kidney transplant may be successful and female donors to male recipients are not suggested, especially in aged patients with the history of dialysis.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945634 | PMC |
| http://dx.doi.org/10.1186/s12882-019-1670-x | DOI Listing |
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