Catalytically Active Peptide-Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes.

Angew Chem Int Ed Engl

Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Takustraße 3, 14195, Berlin, Germany.

Published: June 2020

AI Article Synopsis

  • The self-assembly of peptides onto gold nanoparticles can create artificial enzymes that show improved catalytic abilities.
  • High peptide density around the nanoparticles enhances their effectiveness through cooperative interactions, leading to faster reaction rates.
  • The review highlights advancements in peptide-gold nanoparticle conjugates, explaining their unique features and potential real-world applications.

Article Abstract

The self-assembly of peptides onto the surface of gold nanoparticles has emerged as a promising strategy towards the creation of artificial enzymes. The resulting high local peptide density surrounding the nanoparticle leads to cooperative and synergistic effects, which result in rate accelerations and distinct catalytic properties compared to the unconjugated peptide. This Minireview summarizes contributions to and progress made in the field of catalytically active peptide-gold nanoparticle conjugates. The origin of distinct properties, as well as potential applications, are also discussed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318681PMC
http://dx.doi.org/10.1002/anie.201908625DOI Listing

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