Six individuals who had complete cerebral commissurotomy for medically intractable epilepsy participated in a magnetic resonance imaging study 20 or more years postoperatively. In all cases the completeness of callosotomy was clearly demonstrable. The status of the anterior commissure, cut in all six, could not be confirmed with the same confidence.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1001/archneur.1988.00520350041013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Outcomes following resective and disconnective strategies in the treatment of epileptic spasms: a systematic review of the literature and individual patient data meta-analysis.
Front Neurol
December 2024
Brain and Development Research Axis, Azrieli CHU Ste-Justine Research Center, Montreal, QC, Canada.
Epileptic spasms (ES) are a unique seizure type typically presenting in the form of infantile epileptic spasms syndrome (IESS) with characteristic hypsarrhythmia on scalp EEG and a preponderance with developmental delay or regression. While pharmacotherapy is the mainstay of treatment, surgical options, including disconnective or resective procedures, are increasingly recognized as viable therapeutic options for recurrent or persistent ES. However, limited data on safety, effectiveness, and prognostic factors hinder informed decision-making regarding surgery indications, timing, and intervention type.
View Article and Find Full Text PDFCorpus callosotomy for intractable epilepsy: a contemporary series of operative factors and the overall complication rate.
J Neurosurg Pediatr
December 2024
Departments of1Neurosurgery and.
Objective: Corpus callosotomy is an effective treatment for atonic seizures in patients with medically refractory epilepsy. A large modern series of corpus callosotomies performed via open craniotomy highlights the importance of establishing contemporary complication rates for this operation as a benchmark for comparison with newer methodologies. The authors' study, therefore, examined operative factors and complication rates for a sample of patients who underwent open microsurgical craniotomy for corpus callosotomy to determine current metrics regarding safety and effectiveness for this procedure.
View Article and Find Full Text PDFAge changes in Corpus Callosum among Indian cadaver specimens: a normative study.
Clin Ter
November 2024
Department of Diagnostic and Interventional Radiology, AIIMS, Jodhpur, India.
Background: During neurosurgeries like corpus callosotomy (palliative procedure performed in case of intractable seizures) surgical separation of corpus callosum is required. In order to perform the surgical separation of corpus callosum, one needs to have complete knowledge about anatomy and morphometry of corpus callosum. The current study was carried out in order to establish the normative data about morphometry of corpus callosum across various age groups.
View Article and Find Full Text PDFCorpus callosotomy for refractory epileptic spasms: Systematic review and meta-analysis.
Seizure
December 2024
Epilepsy Program, Division of Neurology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Objective: We systematically reviewed the existing literature on the efficacy of corpus callosotomy (CC) in children and adults with refractory epileptic spasms (ES) and analyzed clinical determinants of seizure outcomes.
Methods: The Preferred Report Items for Systematic Reviews and Meta-Analysis Guidelines (PRISMA) were followed. We systematically searched MEDLINE, EMBASE and Cochrane databases up to December 2023 for original research articles on using CC to treat refractory ES.
A Standardized Approach to MRI-Guided Stereotactic Laser Corpus Callosotomy: Technical Description and Pediatric Case Series.
Oper Neurosurg (Hagerstown)
September 2024
Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA.
Background And Objectives: Corpus callosotomy is an effective procedure approach for treating medication-resistant drop seizures, which pose a significant challenge in patients with epilepsy. Laser interstitial thermal therapy offers an alternative to open surgery for performing corpus callosotomy that may limit approach-related comorbidities. Practices vary regarding the number of laser filaments used and staging; outcome data for pediatric patients remain relatively limited.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!