Purpose: To identify the optimal time for the frozen embryo transfer (FET) after oocyte retrieval in freeze-all cycles.
Methods: A retrospective analysis of 977 patients was performed. Implantation, clinical pregnancy and live birth rates were analyzed.
Results: No significant difference was found between the first FET performed in the first menstrual cycle group and performed within the subsequent menstrual cycle group in terms of implantation, pregnancy and live birth rates. To rule out the effect of endometrial thickness, a hierarchical analysis was performed. There were no differences between groups for pregnancy, multiple pregnancy and live birth rates for all ranges of endometrial thickness.
Conclusions: The first FET should be performed once the endometrial thickness has been prepared well rather than delaying until the subsequent menstrual cycles.
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http://dx.doi.org/10.1007/s00404-019-05405-4 | DOI Listing |
Biomedicines
January 2025
First Department of Obstetrics and Gynecology, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece.
Poor ovarian response (POR) remains a significant challenge in the field of assisted reproductive technology (ART), as the quantity and quality of oocytes retrieved directly influence embryo implantation, clinical pregnancy, and live birth rates. Metabolomics has become a valuable tool for elucidating the molecular mechanisms underlying diminished ovarian reserve (DOR) and POR. This review aims to synthesize findings from metabolomic studies examining metabolite expression patterns in serum and follicular fluid samples from women with POR.
View Article and Find Full Text PDFBiomedicines
December 2024
CCRM Genetics, 10290 Ridgegate Circle, Lone Tree, CO 80124, USA.
Abnormally fertilized embryos are often discarded during in vitro fertilization due to the fact that known chromosomal ploidy abnormalities lead to implantation failure or pregnancy loss. The objective of this study was to determine if pronuclear numeration (PN) observed at fertilization check is representative of the true ploidy status of the subsequent developing blastocyst in order to maximize the number of viable embryos available for infertility patients and increase their chances of conception. Upon successful fertilization, pronuclear numeration was noted, and zygotes were cultured to the blastocyst stage.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2025
School of Medicine, Creighton University, 3100 N Central Ave, Phoenix, AZ 85012, USA.
Background: Health inequities begin before birth and are influenced by pregnancy conditions, race/ethnicity, social class, and environment. Research indicates that, in the United States, Black women are significantly more likely to have low-birth-weight babies compared to White women. Interestingly, Hispanic women in the United States do not experience this birth weight inequity.
View Article and Find Full Text PDFPediatr Res
January 2025
Department of Gynaecology and Obstetrics, University of British Columbia (UBC), Vancouver, BC, 590-828 W 10th Ave, Vancouver, BC, V5Z 1M9, Canada.
Background: Prenatal depression is a potentially important fetal exposure as it may alter fetal development and have lasting effects.
Methods: We examined all live births from 2001 to 2012 in British Columbia with follow-up data on the Early Development Instrument (EDI) in Kindergarten. The odds of developmental vulnerability on EDI domains among those with and without depression during pregnancy were estimated.
BMJ Open
January 2025
Department of Statistics, University of Rajshahi, Rajshahi, Bangladesh
Objectives: Caesarean section (CS) delivery is the most common operative obstetric procedure globally. The increasing trend of CS deliveries poses a significant threat to both child and maternal health. The adverse maternal outcomes associated with caesarean delivery represent a substantial public health concern worldwide.
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