Postpneumonic empyema (EMP) may develop in substance abuse patients, requiring prolonged hospitalization. An algorithm that provides quality care and a rational basis for timely surgical intervention would be advantageous. We report our five-year experience with EMP in substance abuse patients and present such a treatment plan. Sixty-one substance abuse patients were treated for EMP. Posteroanterior, lateral, and decubitus x-ray studies were obtained before treatment to assess fluid movement. Chest tubes were placed to drain frank pus and to obtain material for positive smears. X-ray studies and computed tomography were done 24 hours later to assess parenchymal pathology and to detect any multiple loculations. Thirty-three substance abuse patients recovered following initial tube thoracostomy and 7 after a second chest tube was introduced. Twenty-one had multiple loculations and underwent thoracotomy. Twenty of the 21 required extensive debridement or decortication, or both; 2 required lobectomy and 1 pneumonectomy. Chest tubes were removed on an average of 6 +/- 1.5 days. Average postoperative stay was 10.7 +/- 2 days. There were 2 early deaths and 1 late death and no recurrent EMP. Bacteriology findings were nonspecific and often polymicrobial. We conclude that early thoracotomy can be lifesaving in the presence of a benign clinical course.
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http://dx.doi.org/10.1016/s0003-4975(10)64698-x | DOI Listing |
J Ethn Subst Abuse
January 2025
Lahore School of Behavioural Sciences, The University of Lahore, Lahore, Pakistan.
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Pharmacology Department, School of Medicine, University of Valladolid, Valladolid, Spain.
In 2019, intranasal esketamine gained approval as a promising therapy for those individuals grappling with treatment-resistant depression. Both clinical trials and real-world studies have underscored its efficacy in alleviating and remitting depressive symptoms, with sustained benefits observed for nearly 4.5 years.
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January 2025
Service d'addictologie, Hôpitaux universitaires de Genève, 1211 Genève 14.
Addiction medicine is confronting challenges brought about by changes in our modern world, including shifts in the drug market and the increasing digitalization of our environments. This article highlights some of these challenges and explores potential strategies to address them. The field is also advancing through robust research momentum in psychedelic-assisted psychotherapy.
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January 2025
Montefiore Care Management Organization, New York City (Smali, Chung); Department of Child and Adolescent Psychiatry, New York University Grossman School of Medicine, New York City (Finnerty); Department of Psychiatry and Irving Institute for Clinical and Translational Research, Columbia University, and New York State Psychiatric Institute, New York City (Pincus); Behavioral Health Administration, Maryland Department of Health, Baltimore (Talley); Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle (Goldman); private practice, New York City (Woodlock); Department of Psychiatry, Albert Einstein College of Medicine, New York City (Chung).
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Psychiatr Serv
January 2025
Westat, Rockville, Maryland (Ghose, Beehler, Crocker, Hoey, Masiakowski, Karakus); National Association of State Mental Health Program Directors Research Institute, Falls Church, Virginia, and Department of Psychiatry, University of Michigan, Ann Arbor (Pinals); Department of Psychiatry, University of Maryland, College Park (Goldman); Center for Mental Health Services (Thomas) and Office of the Assistant Secretary for Mental Health and Substance Use (Patel), Substance Abuse and Mental Health Services Administration (SAMHSA), Rockville, Maryland.
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