We report 2 generalized verrucosis (GV) patients homozygous for a novel mutation in the start codon of IL7. Unlike the previous report in which IL-7 deficiency accompanied CD4 T lymphocytopenia, circulating CD4 T cells were not depleted in one of our patients, suggesting a GV pathogenesis other than poor T-cell development.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/cid/ciz1240 | DOI Listing |
Publication Analysis
Top Keywords
generalized verrucosis
8
cases interleukin-7-deficient
4
interleukin-7-deficient generalized
4
verrucosis report
4
report generalized
4
verrucosis patients
4
patients homozygous
4
homozygous novel
4
novel mutation
4
mutation start
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!