AI Article Synopsis
- The study investigates the levels of perlecan, an extracellular matrix proteoglycan linked to endothelial functions, in maternal serum among women with different severities of preeclampsia.
- The research involved 50 women diagnosed with preeclampsia and 30 healthy pregnant women, finding significantly higher serum perlecan levels in those with severe preeclampsia compared to other preeclamptic patients.
- No significant differences in serum perlecan levels were observed between early-onset, late-onset preeclampsia, and healthy pregnancies, indicating that severe preeclampsia is notably distinct.
Article Abstract
: Perlecan is an extracellular matrix proteoglycan suggested to maintain endothelial functions. We aimed to measure maternal serum perlecan levels in different preeclampsia phenotypes.: This study included 50 women with preeclampsia and 30 healthy pregnant women.: Serum perlecan levels were significantly higher (p = 0.016) in preeclamptic women with severe features(n = 23) than preeclampsia patients(n = 27). There were no statistically significant differences in serum perlecan levels between the early-onset preeclampsia(n = 25), late-onset preeclampsia(n = 25), and healthy pregnancies.: Our findings suggest that preeclamptic women with severe features have higher serum perlecan levels than women with preeclampsia.
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| http://dx.doi.org/10.1080/10641955.2019.1711390 | DOI Listing |
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Article Synopsis
- The study investigates the levels of perlecan, an extracellular matrix proteoglycan linked to endothelial functions, in maternal serum among women with different severities of preeclampsia.
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