Purpose: This study aimed to prospectively assess tear dynamics in soft contact lens-induced dry eye while wearing and after removing the soft contact lenses.
Materials And Methods: We analyzed 17 right eyes of soft contact lens users at Wada Eye Clinic (11 men, 6 women; mean age: 36.8 ± 8.3 years; range: 24-57 years). Participants were divided into two groups depending on presence of dry eye symptoms. Video interferometry was used to observe tear dynamics while wearing and after removing soft contact lenses. Interference images focusing on tear spread and interference fringe were compared between groups.
Results: This study included 10 symptomatic and 7 asymptomatic eyes. Considering the symptomatic eyes, while wearing soft contact lenses, 8 eyes showed poor tear spread and multicolor interference fringe, i.e., swift flow of multicolor interference waves after a grayish monochromatic band-color after a blink, but 8 and 10 eyes showed good tear spread and a grayish monochromatic interference fringe when soft contact lenses were removed, respectively. As for asymptomatic eyes, 6 eyes exhibited good tear spread and a grayish monochromatic interference fringe while wearing soft contact lenses and after removing soft contact lenses.
Conclusions: soft contact lens-induced dry eye was associated with tear dynamics only while wearing soft contact lenses. Observation of tear film dynamics in eyes with soft contact lenses could facilitate the understanding of dry eye-related symptoms.
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http://dx.doi.org/10.1080/02713683.2019.1700530 | DOI Listing |
Eur Phys J E Soft Matter
January 2025
Center for Life Nano Science@La Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Rome, Italy.
Understanding the values and origin of fundamental physical constants, one of the grandest challenges in modern science, has been discussed in particle physics, astronomy and cosmology. More recently, it was realized that fundamental constants have a biofriendly window set by life processes involving motion and flow. This window is related to intrinsic fluid properties such as energy and length scales in condensed matter set by fundamental constants.
View Article and Find Full Text PDFBiomater Sci
January 2025
Research Institute for Biomimetics and Soft Matter, Fujian Provincial Key Laboratory for Soft Functional Materials Research, Department of Physics, College of Physical Science and Technology, Xiamen University, Xiamen 361005, China.
Nature-inspired superhydrophobic materials have attracted considerable interest in blood-contacting biomedical applications due to their remarkable water-repellent and self-cleaning properties. However, the interaction mechanism between blood components and superhydrophobic surfaces remains unclear. To explore the effect of trapped air on platelet adhesion, we designed four distinct hydrophobic titanium dioxide (TiO) nanostructures with different fractions of trapped air.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Virginia, Charlottesville, VA, USA.
Background: The microvasculature of the central nervous system (CNS), which delivers oxygen and nutrients and forms a critical barrier protecting the CNS, is deleteriously affected by both Alzheimer's Disease (AD) and Type 2 Diabetes (T2D). Previous studies have shown pericyte dropout and vessel constriction in brain capillaries in AD, while other studies have shown pericyte bridging and dropout in retinal capillaries in T2D. T2D patients have increased risk of AD, suggesting potentially related microvascular pathological mechanisms.
View Article and Find Full Text PDFJ Chem Phys
January 2025
Graduate School of Engineering, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba, Chiba 263-8522, Japan.
Organic multilayer systems, which are stacked layers of different organic materials, are used in various organic electronic devices such as organic light-emitting diodes (OLEDs) and organic field-effect transistors (OFETs). In particular, OFETs are promising as key components in flexible electronic devices. In this study, we investigated how the inclusion of an insulating tetratetracontane (TTC) interlayer in ambipolar indigo-based OFETs can be used to alter the crystallinity and electrical properties of the indigo charge transport layer.
View Article and Find Full Text PDFThe widespread demand for battery-powered technologies has propelled the search for efficient and commercially viable electrode materials with fast-charging abilities. Reported herein is an MoS2-expanded graphite (EG) composite as a stable and high-rate lithium-ion battery (LIB) anode, delivering specific capacities of 796 mAh g-1 at 0.5 A g-1 and 320 mAh g-1 at 20 A g-1 over 400 cycles.
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