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Classifications of haemodialysis vascular access stenosis: a scoping review.
BMJ Open
January 2025
Charles University Third Faculty of Medicine, Prague, Czech Republic
Objectives: Vascular access (VA) stenoses play a significant role in the morbidity of the haemodialysed population. Classifications for diagnosis, assessment and proposal of treatment strategies can be useful clinical and methodological tools. This review aims to present a comprehensive summary and propose further methodological approaches.
View Article and Find Full Text PDFExperimental and theoretical investigation of cyclohexanone derivative (CHD) as a corrosion inhibitor for mild steel in 1 M HCl.
Sci Rep
January 2025
Department of Chemistry, Sahyadri Science College, Shivamogga, Karnataka, 574146, India.
Newly synthesized 1-bromo-2-(4-bromophenylsulfonate)-4,4-dimethyl-1-cyclohexenyl-6-one (CHD) as a potential anticorrosive agent in an acidic medium at an elevated temperature range of 305-335 K. This synthesized compound confirmed by spectral characterizations and it acts as a coating on mild steel surfaces in 1 M Hydrochloric acid (HCl) solution through electrochemical reactions. The synthesis of the compound has been discussed, and the Infrared (IR) and Nucleic Magnetic Resonance (NMR) spectral analysis confirmed the derivative.
View Article and Find Full Text PDFHigh cumulative glucocorticoid dose is associated with increased levels of inflammation-related mediators in active rheumatoid arthritis.
Front Immunol
January 2025
Department of Immunology, Faculty of Medicine and Dentistry, Palacký University Olomouc and University Hospital, Olomouc, Czechia.
Introduction: Glucocorticoids (GCs) are widely used as a treatment for rheumatoid arthritis (RA), leading to high cumulative doses in long-term treated patients. The impact of a high cumulative GC dose on the systemic inflammatory response in RA remains poorly understood.
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Association of triglyceride glucose-body mass index and left ventricular hypertrophy in patients with IgA nephropathy: a retrospective study.
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Department of Nephrology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Introduction: IgA nephropathy (IgAN) is one of the most prevalent forms of glomerulonephritis worldwide, particularly affecting 40-50% of the East Asian population. Cardiovascular mortality represents a leading cause of death in patients with IgAN. Left ventricular hypertrophy (LVH) serves as a predictor of heart failure and cardiovascular mortality.
View Article and Find Full Text PDFRole of TLR4 activation and signaling in bone remodeling, and afferent sprouting in serum transfer arthritis.
Arthritis Res Ther
December 2024
Department of Medicine, University of California, 9500 Gilman Dr. MC 0663, La Jolla, San Diego, CA, USA.
Background: In the murine K/BxN serum transfer rheumatoid arthritis (RA) model, tactile allodynia persists after resolution of inflammation in male and partially in female wild type (WT) mice, which is absent in Toll-like receptor (TLR)4 deficient animals. We assessed the role of TLR4 on allodynia, bone remodeling and afferent sprouting in this model of arthritis.
Methods: K/BxN sera were injected into male and female mice with conditional or stable TLR4 deletion and controls.
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