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Background: Quadriceps dysfunction is ubiquitous after anterior cruciate ligament (ACL) reconstruction (ACLR). Addressing quadriceps dysfunction is crucial to improve function, reduce the reinjury risk, and maintain long-term knee health. While deficits specific to the quadriceps are well documented, less is known about the effect of an ACL injury on other lower extremity muscle groups.
View Article and Find Full Text PDFTrends in Atypical Ductal Hyperplasia Diagnosis and Upgrade: A 20-Year Experience and Impact of MRI Use on Upgrade Rates.
Ann Surg Oncol
January 2025
Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Background: Atypical ductal hyperplasia (ADH) is a benign proliferative breast lesion. Surgical excision of ADH is often recommended to rule out underlying malignant disease.
Objective: The aim of this study was to evaluate the trends in ADH upgrade rates over time and identify the impact of magnetic resonance imaging (MRI) use on upgrade rates.
Symptom-based depression subtypes: brain dynamic specificity and its association with gene expression profiles.
Transl Psychiatry
January 2025
Department of Radiology, Shenzhen Nanshan People's Hospital, Taoyuan AVE 89, Nanshan district, Shenzhen, 518000, People's Republic of China.
At least 227 combinations of symptoms meet the criteria for Major Depressive Disorder (MDD). However, in clinical practice, patients consistently present symptoms in a regular rather than random manner, and the neural basis underlying the MDD subtypes remains unclear. To help clarify the neural basis, patients with MDD were clustered by symptom combinations to investigate the neural underpinning of each subtype using functional resonance imaging (fMRI).
View Article and Find Full Text PDFBrown adipose tissue is associated with reduced weight loss and risk of cancer cachexia: A retrospective cohort study.
Clin Nutr
December 2024
Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, UK; Department of Nutrition, University of California Davis, Davis, CA, USA; Department of Radiology, University of California Davis, Sacramento, CA, USA; Department of Nutritional Sciences and Dietetics, Harokopio University of Athens, Greece. Electronic address:
Background & Aims: Brown adipose tissue (BAT) has been mainly investigated as a potential target against cardiometabolic disease, but it has also been linked to cancer-related outcomes. Although preclinical data support that BAT and the thermogenic adipocytes in white adipose tissue may play an adverse role in the pathogenesis of cancer cachexia, results from studies in patients have reported inconsistent results. The purpose of this study was to examine the interrelationship between presence of detectable BAT, changes in body weight, and cachexia in patients with cancer.
View Article and Find Full Text PDFHigh risk and low incidence diseases: Stercoral colitis.
Am J Emerg Med
January 2025
Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, United States of America.
Introduction: Stercoral colitis is a rare but serious diagnosis which is associated with a high rate of morbidity.
Objective: This review highlights the pearls and pitfalls of stercoral colitis, including presentation, diagnosis, and emergency department (ED) management based on the available evidence.
Discussion: Stercoral colitis is an uncommon inflammatory condition of the distal large bowel and rectum resulting from accumulation of impacted stool and is associated with several complications including bowel ulceration, ischemia, perforation, peritonitis, and sepsis.
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