AI Article Synopsis
Article Abstract
The influence of the tongue on craniofacial growth was studied in 96 miniature pigs MINI-LEWE. The animals were partially glossectomized at different ages and slaughtered at various post-operative intervals. The skulls were macerated for biometric analysis. Mandibular growth in length was significantly reduced in the animals glossectomized at an age of 12 weeks. Both the overall length and that of the tooth-bearing portion were affected.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Achondroplasia, the most prevalent short-stature disorder, is caused by missense variants overactivating the fibroblast growth factor receptor 3 (FGFR3). As current surgical and pharmaceutical treatments only partially improve some disease features, we sought to explore a genetic approach. We show that an enhancer located 29 kb upstream of mouse Fgfr3 (-29E) is sufficient to confer a transgenic mouse reporter with a domain of expression in cartilage matching that of Fgfr3.
View Article and Find Full Text PDFA new harmony box supplemented with gonial angle and age based on a growing Swiss population.
J Orofac Orthop
January 2025
Clinic of Orthodontics and Pediatric Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032, Zurich, Switzerland.
Purpose: The scope of the present study was to create a new harmony box by adding two diagnostically and clinically important cephalometric variables, the gonial and interincisal angles, while also considering the effect of sex and age for a growing Swiss population.
Methods: A healthy sample with an overjet and overbite between 2 and 4 mm, and 1.5 and 4.
Nerves at Play: The Peripheral Nervous System in Extracranial Malignancies.
Cancer Discov
January 2025
Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
The exponential growth of the cancer neuroscience field has shown that the host's immune, vascular, and nervous systems communicate with and influence each other in the tumor microenvironment, dictating the cancer malignant phenotype. Unraveling the nervous system's contributions toward this phenotype brings us closer to cancer cures. In this review, we summarize the peripheral nervous system's contributions to cancer.
View Article and Find Full Text PDFObjectives: To compare differences in craniofacial growth prediction results for Korean and American children according to growth prediction models developed using Korean and American longitudinal growth data.
Materials And Methods: Growth prediction models based on cephalometric landmarks were built for each population using longitudinally taken lateral cephalograms of Korean children and American children of northern European origin. The sample sizes of the serial datasets were 679 and 1257 for Korean and American children, respectively.
Identification of the Determinants of Plexiform Neurofibroma Morbidity in Pediatric and Young Adult Neurofibromatosis Type 1 Patients: A Pilot Multivariate Approach.
Cancers (Basel)
January 2025
Sophia, Department of General Pediatrics, Erasmus MC, 3015 GD Rotterdam, The Netherlands.
Background: Plexiform neurofibromas (PNs) are histologically benign peripheral nerve sheath tumors associated with neurofibromatosis type 1 (NF1) and often lead to significant morbidity due to growth. Management includes watchful waiting, surgery for partial debulking, and, since recently, systemic treatment with MEK inhibitors. However, due to the scarcity of natural history studies, our understanding of the natural progression of PNs to guide clinicians in deciding in whom and when to intervene is scarce.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!