Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019190PMC
http://dx.doi.org/10.1182/blood.2019003570DOI Listing

Publication Analysis

Top Keywords

achieving complete
4
complete remission
4
remission cll
4
cll patients
4
patients treated
4
treated ibrutinib
4
ibrutinib clinical
4
clinical significance
4
significance predictive
4
predictive factors
4

Similar Publications

Differences in the efficiency and mechanisms of different iron-based materials driving synchronous nitrogen and phosphorus removal.

Environ Res

December 2024

State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, No. 73 Huanghe Road, Nangang District, Harbin 150090, China. Electronic address:

Iron-dependent denitrification has been substantially investigated worldwide due to the advantages of low cost, high efficiency, and synchronized phosphorous removal. However, differences in nitrogen metabolism processes with different iron-based materials as electron donors have not been systematically studied. This study investigated the efficacy of nitrogen and phosphate removal using various iron-based materials as electron donors.

View Article and Find Full Text PDF

Neoadjuvant and adjuvant osimertinib in stage IA-IIIA, EGFR-mutant non-small cell lung cancer (NORA).

J Thorac Oncol

December 2024

Division of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

Introduction: Treatment with adjuvant osimertinib for three years is the standard-of-care for resected stage IB-IIIA non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR)-mutations. The role of neoadjuvant osimertinib in the perioperative setting is yet to be elucidated in the NeoADAURA study (NCT04351555).

Methods: This is a single center, pilot study of patients with clinical stage IA-IIIA NSCLC (AJCC 8th edition) harboring an activating EGFR mutation (Exon 19 deletion, L858R) (NCT04816838).

View Article and Find Full Text PDF

Purpose: To assess whether capsular closure during hip arthroscopy with periportal capsulotomy affects 2-year postoperative outcomes for femoroacetabular impingement syndrome (FAIS) patients without hypermobility.

Methods: A matched-cohort retrospective analysis of a single institutional database of patients who underwent hip arthroscopy with periportal capsulotomy for management of FAIS between 2014-2022 was performed. Study inclusion criteria consisted of FAIS patients who exhibited no signs of generalized ligamentous laxity (GLL) (Beighton score 0).

View Article and Find Full Text PDF

Background: Female soccer athletes with a history of anterior cruciate ligament injury are more susceptible to secondary injuries and potentially worse sport performance. The purpose of this study was to determine if female soccer athletes post anterior cruciate ligament reconstruction demonstrate worse jump height and reactive strength index performance and lower involved limb hip, knee, and ankle joint power and absorption, and larger joint power and absorption asymmetries compared to matched uninjured athletes.

Methods: Eleven Division I female soccer athletes post anterior cruciate ligament reconstruction (18.

View Article and Find Full Text PDF

Designing of new trans-stilbene derivative: An entry barrier of Zika virus in host cell.

J Mol Graph Model

December 2024

Post Graduate Department of Chemistry, Mehr Chand Mahajan DAV College for Women, Chandigarh, 160036, India.

A large population in the world lives in tropical and subtropical regions, showing a high risk of Zika viral infection which leads to a situation of global health emergency and demands extensive research to create effective antiviral medicines. Herein, we introduce the design of a new derivatized trans-stilbene molecule to investigate the inhibition of Zika virus entry into the host cell by molecular docking approach. The synthesized compound has been characterized by different analytical techniques such as FTIR, H NMR,C NMR and UV-visible spectroscopy as well as Mass spectrometry (MS).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!