Objective: We examined individual overall trajectories of change and the occurrence of sudden gains in daily self-rated problem severity and the relation of these patterns to treatment response.
Method: Mood disorder patients ( = 329, mean age = 44, 55% women) completed daily self-ratings about the severity of their complaints as a standard part of treatment, using the Therapy Process Questionnaire (TPQ). Per individual, the best-fitting defined (linear, log-linear, 1-step) trajectory was tested for significance: for change over time, and for specificity of the best-fitting trajectory. Two-hundred and three cases had ICD-10 Symptom Rating (ISR) depression scores posttreatment: a score ≤1 identified 114 treatment responders. Relation to response was examined for sudden gains and type of change trajectory.
Results: 138 cases (42%) had a significant decrease in problem severity, of which 54 cases (16%) had a defined trajectory: 50 cases with one-step improvement, and 4 with a linear improvement in daily problem severity. Sudden gains occurred in 28% of the total sample, and within 58% of improvement patterns. Specifically, sudden gains occurred in 68% of significant 1-step trajectories and 25% of the linear cases. Sudden gains and nonspecific change trajectories were significantly more frequent for treatment responders.
Conclusions: At the day-level, patterns of improvement are nonlinear for most patients. Sudden gains occur within various forms of overall change and are associated with treatment response. Clinically relevant improvements in depression occur both gradually and abruptly, and this finding allows for the possibility that the remission process functions according to dynamical systems principles. (PsycINFO Database Record (c) 2020 APA, all rights reserved).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1037/ccp0000469 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bone Stress Injuries: Diagnosis and Management.
Am Fam Physician
December 2024
Hugo V. Mendoza Soldier Family Care Center at Fort Bliss, Texas.
Article Synopsis
- - Bone stress injuries (BSIs) are overuse injuries that occur when there's repetitive strain on bone, either from excessive physical activity on healthy bone or normal activity on already weakened bone, often seen in younger athletes and those with medical conditions affecting bone density.
- - Stress fractures are a severe form of BSIs, representing about 20% of cases and show clear signs on imaging; untreated, they can lead to complete fractures, with the main symptoms being localized pain and tenderness in response to increased physical loads.
- - Treatment involves early intervention, focusing on modifying risk factors like nutrition and activity; imaging such as X-rays and MRIs help confirm BSIs, with management approaches varying based on the injury's severity and location, necessitating specialist
A Technique for Monitoring Mechanically Ventilated Patient Lung Conditions.
Diagnostics (Basel)
November 2024
Faculty of Engineering, North-West University, Potchefstroom 2531, South Africa.
Background: Mechanical ventilation is a critical but resource-intensive treatment. Automated tools are common in screening diagnostics, whereas real-time, continuous trend analysis in mechanical ventilation remains rare. Current techniques for monitoring lung conditions are often invasive, lack accuracy, and fail to isolate respiratory resistance-making them impractical for continuous monitoring and diagnosis.
View Article and Find Full Text PDFExpand the Success of Screening to Reduce Aortic Aneurysm Mortality - Progress Interpretation and New Fronts.
Trends Cardiovasc Med
December 2024
Division of Molecular Medicine, Department of Anesthesiology and Perioperative Medicine, Division of Cardiology, Department of Medicine, David Geffen School of Medicine. Electronic address:
Aortic aneurysm is a leading cause of death across the world. Many victicms carry it without knowing. Ruputre of aortic aneurysms leads to devastating sudden death.
View Article and Find Full Text PDFThe Relationship between Chronic Unilateral Hearing Loss, Balance Function, and Falls Is Not Informed by Vestibular Status.
Otol Neurotol
December 2024
Department of Applied Statistics, Social Science, and Humanities, New York University, New York.
Objectives: Recent studies suggest that hearing loss is associated with balance dysfunction and an increased risk of falls. The purpose of this study was to investigate whether adults with unilateral hearing loss (UHL) have an underlying vestibular dysfunction and whether vestibular testing explains balance function and fall risk.
Study Design: Cross-sectional.
Cytokine release syndrome caused by immune checkpoint inhibitors: a case report and literature review.
Future Sci OA
December 2024
Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Immune checkpoint inhibitors (ICIs) have gained widespread application in the treatment of malignant tumors. Cytokine release syndrome (CRS) is a systemic inflammatory response triggered by various factors, including infections and immunotherapy. We present a case of CRS occurring in a gastric cancer patient after receiving combination therapy of tislelizumab, anlotinib and combination of capecitabine and oxaliplatin.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!