Coronary lithoplasty is a promising technique that can overcome issues regarding the treatment of undilatable, heavily calcified, de novo, and in-stent restenotic lesions, allowing plaque modification and successful stent deployment, as demonstrated by intravascular imaging.
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Impact of lesion preparation-induced calcified plaque defects in vascular intervention for atherosclerotic disease: in silico assessment.
Biomech Model Mechanobiol
January 2025
Cardiac Surgery Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Percutaneous coronary interventions in highly calcified atherosclerotic lesions are challenging due to the high mechanical stiffness that significantly restricts stent expansion. Intravascular lithotripsy (IVL) is a novel vessel preparation technique with the potential to improve interventional outcomes by inducing microscopic and macroscopic cracks to enhance stent expansion. However, the exact mechanism of action for IVL is poorly understood, and it remains unclear whether the improvement in-stent expansion is caused by either the macro-cracks allowing the vessel to open or the micro-cracks altering the bulk material properties.
View Article and Find Full Text PDFSuccessful calcium modification of a large calcified nodule using shockwave intravascular lithotripsy in the setting of acute coronary syndrome: a case report.
Eur Heart J Case Rep
October 2024
Cardiovascular Department, Al Qassimi Hospital, Sharjah, 3500, UAE.
Background: Calcified nodules are associated with suboptimal preparation before stenting due to challenging crossing and unsuccessful pre-dilation and calcium cracking with conventional balloons. In this scenario, we report the use of shockwave intravascular lithotripsy for the successful lesion preparation of an undilatable and challenging calcified nodule in a patient presenting with ACS.
Case Summary: We report a case of a 79-year-old male patient presented with non-ST elevation myocardial infarction.
Complete Resolution of Plantar Psoriasis With Ayurveda, A Case Report.
Altern Ther Health Med
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Background: Palmoplantar psoriasis is a type of psoriasis that primarily affects the palms and soles, characterized by erythematous plaques, scaling, and fissuring. These features can significantly impair the quality of life, varying in severity. Skin disorders often result from lifestyle changes, such as consuming an incompatible diet (Viruddha Ahaar Sewan refers to eating foods in a contradictory order or that vitiate the body's Doshas), unhealthy food habits and a sedentary lifestyle.
View Article and Find Full Text PDFIntroduction: Psoriasis which affects the skin of palm and soles is called as Palmoplantar Psoriasis. The exact cause of it is unknown. It has predominantly hyperkeratotic plaques, thick scaly skin or an overlapping of both of them.
View Article and Find Full Text PDFMI-CSBO: a hybrid system for myocardial infarction classification using deep learning and Bayesian optimization.
Comput Methods Biomech Biomed Engin
July 2024
Gaziantep Emek Hospital, Gaziantep, Turkey.
Myocardial Infarction (MI) refers to damage to the heart tissue caused by an inadequate blood supply to the heart muscle due to a sudden blockage in the coronary arteries. This blockage is often a result of the accumulation of fat (cholesterol) forming plaques (atherosclerosis) in the arteries. Over time, these plaques can crack, leading to the formation of a clot (thrombus), which can block the artery and cause a heart attack.
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