AI Article Synopsis
- - The study investigated the epidemiology of intracranial aneurysms in Brazil, involving 1404 patients admitted to a major hospital between 2009 and 2018, looking at factors like location, gender, age, and comorbidities.
- - A total of 2251 aneurysms were identified, with a higher prevalence in females (77.6%), an average diagnosis age of 54.9 years, and the most common locations being the middle cerebral artery and anterior cerebral artery.
- - Significant findings included that multiple aneurysms were more often seen in females and smokers, while the relationship between hypertension and multiple aneurysms was not statistically significant.
Article Abstract
Background: We sought to evaluate the epidemiology of intracranial aneurysms in relation to location, gender, age, presence of multiple aneurysms, and comorbidities in the Brazilian population.
Methods: We performed a prospective analysis of a cohort of 1404 patients diagnosed with intracranial aneurysm admitted to the Hospital das Clinicas of the University of Sao Paulo, a referral hospital for the treatment of cerebrovascular diseases in Brazil. Patients admitted between September 2009 and September 2018 with radiological diagnosis of intracranial aneurysm were included in the study.
Results: A total of 2251 aneurysms were diagnosed. Females accounted for 1090 aneurysms (77.6%) and the mean age at diagnosis was 54.9 years (ranging 15-88). The most common location was middle cerebral artery (MCA) with 593 aneurysms (26.3%) followed by anterior cerebral artery (ACA) with 417 aneurysms (18.5%) and internal carotid artery in the posterior communicating segment with 405 aneurysms (18.0%). Males had higher rates of ACA aneurysms (29.7%) while females had higher rates of MCA aneurysms (26.1%). Sorting by size, 492 aneurysms were <5 mm (21.8%), 1524 measured 5-10 mm (67.7%), 119 size 11-24 mm (5.3%), and 116 were >24 mm (5.2%). The occurrence of multiple aneurysms was associated with female gender ( < 0.001) and smoking ( < 0.001), but not with hypertension ( = 0.121).
Conclusion: In this population, the occurrence of intracranial aneurysm is related to several factors, including gender, age, smoking, and hypertension. Our study brought to light important characteristics of a large number of Brazilian patients regarding epidemiology, location, size, and multiplicity of intracranial aneurysms.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935967 | PMC |
| http://dx.doi.org/10.25259/SNI_443_2019 | DOI Listing |
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