A 71-year-old man with recurrent pulmonary mycobacterial avium complex infections and lymphopenia.

Allergy Asthma Proc

From the Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington.

Published: January 2020

AI Article Synopsis

  • Mycobacterium avium complex (MAC) infections are typically seen as opportunistic, raising concerns about underlying immune system issues.
  • These infections can also affect patients who otherwise have a normal immune response, especially those with structural lung problems.
  • The case presented involves a patient with low T-cell levels (lymphopenia) complicating their pulmonary MAC infection, despite being negative for HIV.

Article Abstract

Mycobacterium avium complex (MAC) infections, generally viewed as opportunistic infections, often trigger an evaluation for an underlying immunodeficiency disorder. However, MAC infections can occur in patients who presumably are immunocompetent, particularly in those with an underlying structural lung disease. T-cell immunity plays a critical role in controlling MAC infection. We presented a case of lymphopenia, which complicated the clinical course of a pulmonary MAC infection in a patient who was negative for human immunodeficiency virus.

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Source
http://dx.doi.org/10.2500/aap.2020.41.190003DOI Listing

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