AI Article Synopsis
- A study was conducted in Haiti from 2015-2017 to evaluate the effectiveness of case-area targeted interventions (CATIs) against cholera during 238 identified outbreaks.
- Research showed that prompt responses to cholera outbreaks resulted in a 76% reduction in accumulated cases and a 61% decrease in outbreak duration compared to delayed responses.
- Intense responses also demonstrated significant effectiveness, reducing cases by 59% and outbreak duration by 73% compared to weaker responses, indicating that timely and vigorous interventions are crucial in managing cholera outbreaks.
Article Abstract
Case-area targeted interventions (CATIs) against cholera are conducted by rapid response teams, and may include various activities like water, sanitation, hygiene measures. However, their real-world effectiveness has never been established. We conducted a retrospective observational study in 2015-2017 in the Centre department of Haiti. Using cholera cases, stool cultures and CATI records, we identified 238 outbreaks that were responded to. After adjusting for potential confounders, we found that a prompt response could reduce the number of accumulated cases by 76% (95% confidence interval, 59 to 86) and the outbreak duration by 61% (41 to 75) when compared to a delayed response. An intense response could reduce the number of accumulated cases by 59% (11 to 81) and the outbreak duration by 73% (49 to 86) when compared to a weaker response. These results suggest that prompt and repeated CATIs were significantly effective at mitigating and shortening cholera outbreaks in Haiti.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041943 | PMC |
| http://dx.doi.org/10.7554/eLife.50243 | DOI Listing |
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