Utilizing mice with swollen lymph nodes, we succeeded in irradiating individual metastatic lymph nodes through a hole in a lead shield. This system enabled us to increase the radiation dose to >8 Gy (the lethal dose for total-body irradiation) and evaluate both direct and abscopal antitumor effects.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921225 | PMC |
| http://dx.doi.org/10.1016/j.ctro.2019.05.002 | DOI Listing |
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