Fractal processes have recently received a growing interest, especially in the domain of rehabilitation. More precisely, the evolution of fractality with aging and disease, suggesting a loss of complexity, has inspired a number of studies that tried, for example, to entrain patients with fractal rhythms. This kind of study requires relevant methods for generating fractal signals and for assessing the fractality of the series produced by participants. In the present work, we engaged a cross validation of three methods of generation and three methods of analysis. We generated exact fractal series with the Davies-Harte (DH) algorithm, the spectral synthesis method (SSM), and the ARFIMA simulation method. The series were analyzed by detrended fluctuation analysis (DFA), power spectral density (PSD) method, and ARFIMA modeling. Results show that some methods of generation present systematic biases: DH presented a strong bias toward white noise in fBm series close to the 1/ boundary and SSM produced series with a larger variability around the expected exponent, as compared with other methods. In contrast, ARFIMA simulations provided quite accurate series, without major bias. Concerning the methods of analysis, DFA tended to systematically underestimate fBm series. In contrast, PSD yielded overestimates for fBm series. With DFA, the variability of estimates tended to increase for fGn series as they approached the 1/ boundary and reached unacceptable levels for fBm series. The highest levels of variability were produced by PSD. Finally, ARFIMA methods generated the best series and provided the most accurate and less variable estimates.
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http://dx.doi.org/10.1155/2019/4025305 | DOI Listing |
World Neurosurg
November 2024
Department of Spinal Surgery, Lausanne University Hospital (CHUV), Lausanne, Switzerland; Faculty of Biology and Medicine (FBM), University of Lausanne (UNIL), Lausanne, Switzerland. Electronic address:
J Physiol
June 2024
Center for Behavioral Neuroscience and Communication (BNC), Vita-Salute San Raffaele University, Milan, Italy.
Neurons in the central nervous system communicate with each other by activating billions of tiny synaptic boutons distributed along their fine axons. These presynaptic varicosities are very crowded environments, comprising hundreds of synaptic vesicles. Only a fraction of these vesicles can be recruited in a single release episode, either spontaneous or evoked by action potentials.
View Article and Find Full Text PDFFront Reprod Health
January 2024
Department of Obstetrics and Gynecology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Background: Ulcus Vulvae Acutum Lipschütz (UVAL) is a largely unknown disease with a broad and complex differential diagnosis.
Objectives: To provide a description of the main characteristics of UVAL, determine the most appropriate diagnostic process and describe the current therapeutic approach.
Methods: We designed a retrospective, descriptive cohort study using the gynecological-ER database of our institution.
bioRxiv
November 2023
Department of Statistics & Actuarial Science, University of Waterloo, CA.
The mucus lining of the human airway epithelium contains two gel-forming mucins, MUC5B and MUC5AC. During progression of cystic fibrosis (CF), mucus hyper-concentrates as its mucin ratio changes, coinciding with formation of insoluble, dense mucus flakes. We explore rheological heterogeneity of this pathology with reconstituted mucus matching three stages of CF progression and particle-tracking of 200 nm and 1 micron diameter beads.
View Article and Find Full Text PDFJ Neurooncol
October 2023
Neurosurgery Service and Gamma Knife Center, Centre Hospitalier Universitaire Vaudois (CHUV), Rue du Bugnon 44-46, BH-08, CH-1011, Lausanne, Switzerland.
Purpose: To perform a systematic review of literature specific to single-fraction stereotactic radiosurgery (SRS) for large vestibular schwannomas (VS), maximum diameter ≥ 2.5 cm and/or classified as Koos Grade IV, and to present consensus recommendations on behalf of the International Stereotactic Radiosurgery Society (ISRS).
Methods: The Medline and Embase databases were used to apply the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach.
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