Dodelates A-E: Five dimeric eudesmane sesquiterpenoids from Dobinea delavayi.

Bioorg Chem

Institute of Materia Medica, Dali University, Dali 671000, PR China. Electronic address:

Published: January 2020

Dodelates A-E (1-5), five angeloylated eudesmane sesquiterpenoid dimers were isolated from the roots of Dobinea delavayi. Their structures were elucidated by extensive spectroscopic data and single-crystal X-ray diffraction analyses. A possible biosynthetic pathway of these five compounds was proposed. Compounds 1 and 3 exhibited moderate antimalarial activities against Plasmodium yoelii BY265RFP.

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http://dx.doi.org/10.1016/j.bioorg.2019.103488DOI Listing

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